Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Role of ventilation strategy on perfluorochemical evaporation from the lungs
Autore:
Jeng, MJ; Trevisanuto, D; Weis, CM; Fox, WW; Cullen, AB; Wolfson, MR; Shaffer, TH;
Indirizzi:
Vet Gen Hosp, Childrens Med Ctr, Dept Pediat, Taipei 11217, Taiwan Vet GenHosp Taipei Taiwan 11217 Ctr, Dept Pediat, Taipei 11217, Taiwan Natl Yang Ming Univ, Sch Med, Inst Clin Med, Taipei 112, Taiwan Natl Yang Ming Univ Taipei Taiwan 112 Inst Clin Med, Taipei 112, Taiwan Univ Padua, Dept Pediat, I-35158 Padua, Italy Univ Padua Padua Italy I-35158 Padua, Dept Pediat, I-35158 Padua, Italy Univ Penn, Childrens Hosp Philadelphia, Sch Med, Dept Neonatol, Philadelphia, PA 19140 USA Univ Penn Philadelphia PA USA 19140 Neonatol, Philadelphia, PA 19140 USA Temple Univ, Sch Med, Dept Physiol, Philadelphia, PA 19140 USA Temple Univ Philadelphia PA USA 19140 Physiol, Philadelphia, PA 19140 USA Temple Univ, Sch Med, Dept Pediat, Philadelphia, PA 19140 USA Temple UnivPhiladelphia PA USA 19140 Pediat, Philadelphia, PA 19140 USA
Titolo Testata:
JOURNAL OF APPLIED PHYSIOLOGY
fascicolo: 4, volume: 90, anno: 2001,
pagine: 1365 - 1372
SICI:
8750-7587(200104)90:4<1365:ROVSOP>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
PARTIAL LIQUID VENTILATION; RESPIRATORY-DISTRESS-SYNDROME; GAS-EXCHANGE; DOSE MAINTENANCE; PREMATURE LAMBS; INJURY; SURFACTANT; MODEL; ELIMINATION; PERFLUBRON;
Keywords:
partial liquid ventilation; minute ventilation; elimination; rabbit;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
45
Recensione:
Indirizzi per estratti:
Indirizzo: Jeng, MJ Vet Gen Hosp, Childrens Med Ctr, Dept Pediat, 210,Sect 2,Shih PeiRd, Taipei 11217, Taiwan Vet Gen Hosp 210,Sect 2,Shih Pei Rd Taipei Taiwan 11217 , Taiwan
Citazione:
M.J. Jeng et al., "Role of ventilation strategy on perfluorochemical evaporation from the lungs", J APP PHYSL, 90(4), 2001, pp. 1365-1372

Abstract

To study the effect of ventilation strategy on perfluorochemical (PFC) elimination profile (evaporative loss profile; E-L), 6 mL/kg of perflubron were instilled into anesthetized normal rabbits. The strategy was to maintain minute ventilation (V-E, in ml/min) in three groups: (V) over dot E-L, (low-range (V) over dot E, 208 +/- 2), (V) over dot E-M, (midrange (V) over dotE, 250 +/- 9), and (V) over dot E-H, thigh-range (V) over dot E, 293 +/- 1) over 4 h. In three other groups, respiratory rate (RR, breaths/min) was controlled at 20, 30, or 50 with a constant (V) over dot E and adjusted tidal volume. PFC content in the expired gas was measured, and E, was calculated. There was a significant (V) over dot E- and time-dependent effect on E-LInitially, percent PFC saturation and loss rate decreased in the (V) over dot E-H > (V) over dot E-M > (V) over dot E-L groups, but by 3 h the lower percent PFC saturation resulted in a loss rate such that (V) over dot E-H <(V) over dot E-M < (V) over dot E-L at 4 h. For the groups at constant ire, there was a significant time effect on E, but no RR effect. In conclusion, E, profile is dependent on (V) over dot E with little effect of the RR-tidal volume combination. Thus measurement of E, and VE should be considered for the replacement dosing schemes during partial liquid ventilation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 22:39:12