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Titolo:
Effect of exercise and medium-chain fatty acids on postprandial lipemia
Autore:
Thomas, TR; Horner, KE; Langdon, MM; Zhang, JQ; Krul, ES; Sun, GY; Cox, RH;
Indirizzi:
Univ Missouri, Dept Nutrit Sci, Exercise Physiol Program, Columbia, MO 65211 USA Univ Missouri Columbia MO USA 65211 ysiol Program, Columbia, MO 65211 USA Monsanto Co, Nutr & Consumer Sector, St Louis, MO 63167 USA Monsanto Co St Louis MO USA 63167 Consumer Sector, St Louis, MO 63167 USA Univ Missouri, Dept Biochem, Columbia, MO 65211 USA Univ Missouri Columbia MO USA 65211 Dept Biochem, Columbia, MO 65211 USA
Titolo Testata:
JOURNAL OF APPLIED PHYSIOLOGY
fascicolo: 4, volume: 90, anno: 2001,
pagine: 1239 - 1246
SICI:
8750-7587(200104)90:4<1239:EOEAMF>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHOLESTERYL ESTER TRANSFER; HIGH-DENSITY-LIPOPROTEINS; LIPID TRANSFER PROTEIN; LONG-CHAIN; HEPATIC LIPASE; PLASMA; TRIGLYCERIDES; METABOLISM; HYPERTRIGLYCERIDEMIA; TRIACYLGLYCEROLS;
Keywords:
cholesterol ester transfer protein; exercise training; hepatic lipase activity; lipoprotein lipase activity; triglycerides;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Thomas, TR Univ Missouri, Dept Nutrit Sci, Exercise Physiol Program, 104 Rothwell Gym, Columbia, MO 65211 USA Univ Missouri 104 Rothwell Gym ColumbiaMO USA 65211 65211 USA
Citazione:
T.R. Thomas et al., "Effect of exercise and medium-chain fatty acids on postprandial lipemia", J APP PHYSL, 90(4), 2001, pp. 1239-1246

Abstract

The purpose of this study was to evaluate the effect of medium-chain triglycerides (MCT) with and without exercise on postprandial lipemia (PPL). Subjects were 25 young men and women. Each subject performed three trials: 1) control (fat meal only, 1.5 g fat/kg) 2) MCT (substitution of MCT oil, 30% of fat calories), and 3) MCT + Ex (exercise 12 h before the MCT meal). Before each trial, the subject underwent consistent dietary preparation. Blood was collected on 2 separate days for baseline measurements of postheparin lipases and, in each trial, at 0 h (premeal), at 2, 4, 6, and 8 h after the fat meal for triglycerides and cholesterol ester transfer protein (CETP), and at 8 h for postheparin lipoprotein lipase (LPL) and hepatic lipase activities (HL). ANOVA indicated that the partial substitution of MCT oil to thefat meal did not affect the PPL response. However, the PPL was significantly lower after the MCT + Ex trial vs. the other trials. LPL activity was significantly elevated after all trials compared with baseline, whereas HL was lower in the MCT + Ex trial only. CETP mass was significantly lower at 4 and 8 h than 0 h during all trials but relatively higher in the MCT; Ex trial vs. the nonexercise trials. These results suggest that MCT does not affect the TG response to a fat meal. LPL and CETP are affected by a fat meal with or without exercise, but HL is affected only when exercise is included.

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Documento generato il 22/01/20 alle ore 06:43:11