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Titolo:
An update on the genetics of systemic lupus erythematosus
Autore:
Johanneson, B; Alarcon-Riquelme, ME;
Indirizzi:
Uppsala Univ, Dept Genet & Pathol, Med Genet Sect, Rudbeck Labs, Uppsala, Sweden Uppsala Univ Uppsala Sweden d Genet Sect, Rudbeck Labs, Uppsala, Sweden
Titolo Testata:
ISRAEL MEDICAL ASSOCIATION JOURNAL
fascicolo: 2, volume: 3, anno: 2001,
pagine: 88 - 93
SICI:
1565-1088(200102)3:2<88:AUOTGO>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
SIB-PAIR FAMILIES; SUSCEPTIBILITY GENES; PARP ALLELES; GENOME SCAN; LINKAGE; INTERLEUKIN-10; ASSOCIATION; DISEASE; POLYMORPHISMS; DEFICIENCY;
Keywords:
systemic lupus erythematosus; human genome scans; linkage studies; candidate genes;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Alarcon-Riquelme, ME Uppsala Univ, Dept Genet & Pathol, Med Genet Sect, Rudbeck Labs, Uppsala, Sweden Uppsala Univ Uppsala Sweden Labs, Uppsala, Sweden
Citazione:
B. Johanneson e M.E. Alarcon-Riquelme, "An update on the genetics of systemic lupus erythematosus", ISR MED ASS, 3(2), 2001, pp. 88-93

Abstract

The development of systemic lupus erythematosus has a strong genetic basis. The techniques to study the genetics of SLE have improved, and family-based studies have been gaining importance due to advances in the human genomeproject. Recently, complete genome scans with microsatellite markers and linkage analysis have been performed in human systemic lupus erythematosus in various populations. These studies represent the first step of a process towards the identification of susceptibility genes in SLE. We review here the results of the human genome scans performed until now and provide an update of the latest advances on the genetics of SLE in linkage studies and association analyses of candidate genes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/12/19 alle ore 15:27:11