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Titolo:
Assessment of as needed use of pharmacotherapy and the pause-squeeze technique in premature ejaculation
Autore:
Abdel-Hamid, IA; El Naggar, EA; El Gilany, AH;
Indirizzi:
Mansoura Fac Med, Dept Androl, Mansoura, Egypt Mansoura Fac Med MansouraEgypt a Fac Med, Dept Androl, Mansoura, Egypt Mansoura Fac Med, Dept Psychiat, Mansoura, Egypt Mansoura Fac Med Mansoura Egypt Fac Med, Dept Psychiat, Mansoura, Egypt Mansoura Fac Med, Dept Community Med, Mansoura, Egypt Mansoura Fac Med Mansoura Egypt ed, Dept Community Med, Mansoura, Egypt
Titolo Testata:
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
fascicolo: 1, volume: 13, anno: 2001,
pagine: 41 - 45
SICI:
0955-9930(200102)13:1<41:AOANUO>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
CLOMIPRAMINE; SERTRALINE; MEN;
Keywords:
premature ejaculation; behavioral therapy; antidepressants; sildenafil;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Abdel-Hamid, IA Mansoura Fac Med, Dept Androl, POB 35516, Mansoura, Egypt Mansoura Fac Med POB 35516 Mansoura Egypt ansoura, Egypt
Citazione:
I.A. Abdel-Hamid et al., "Assessment of as needed use of pharmacotherapy and the pause-squeeze technique in premature ejaculation", INT J IMPOT, 13(1), 2001, pp. 41-45

Abstract

The objective was to compare the efficacy and safety of the as needed use of clomipramine, sertraline, paroxetine, sildenafil and the pause-squeeze technique in treatment of primary premature ejaculation. A prospective double blind randomized crossover study involving 31 patients was performed. Treatment phases comprised five 4-week consecutive treatment periods, eachseparated by a two-week washout period, patients were randomly assigned toreceive each of the 4 drugs and use pause-squeeze on an as needed basis. Drugs were administered 3 to 5 hours before anticipated coitus. Anxiety score and ejaculation latency time were measured before treatment, after each treatment, and during washout periods. Sexual satisfaction score was measured after each treatment. The median ejaculation latency time was significantly increased from the pretreatment median of 1 minute to 4 minutes, 3 minutes, 4 minutes, 15 minutes and 3 minutes during treatment with clomipramine, sertraline, paroxetine, sildenafil and pause-squeeze technique, respectively (all P = 0.0001), Sildenafil was superior to other modalities in terms of ejaculation latency and satisfaction (P = 0.0001). The three antidepressants were comparable to each other in terms of efficacy (P > 0.05). Paroxetine was superior to the pause-squeeze technique in terms of efficacy (P < 0.05). In conclusion, sildenafil appears to be superior to other modalities and avalid alternative in treatment of premature ejaculation. The 3 antidepressants were equivalent to each other in terms of efficacy and safety. Paroxetine was superior to pause-squeeze technique in terms of efficacy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 10:21:11