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Titolo:
Pulmonary function and urban air pollution in preschool children
Autore:
Fritz, GJ; Herbarth, O;
Indirizzi:
Univ Leipzig, Fac Med, D-04103 Leipzig, Germany Univ Leipzig Leipzig Germany D-04103 , Fac Med, D-04103 Leipzig, Germany UFZ, Ctr Environm Res Leipzig Halle, Dept Human Exposure Res & Epidemiol, D-04318 Leipzig, Germany UFZ Leipzig Germany D-04318 re Res & Epidemiol, D-04318 Leipzig, Germany
Titolo Testata:
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
fascicolo: 3, volume: 203, anno: 2001,
pagine: 235 - 244
SICI:
1438-4639(200103)203:3<235:PFAUAP>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
VOLATILE ORGANIC-COMPOUNDS; LUNG-FUNCTION; RESPIRATORY SYMPTOMS; BRONCHIAL REACTIVITY; MATERNAL SMOKING; ILLNESS; CHILDHOOD; EXPOSURE; POPULATION; EPISODE;
Keywords:
coal heating; lung function; preschool children; pulmonary restriction; traffic;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
54
Recensione:
Indirizzi per estratti:
Indirizzo: Fritz, GJ Univ Leipzig, Fac Med, Liebigstr 24, D-04103 Leipzig, Germany Univ Leipzig Liebigstr 24 Leipzig Germany D-04103 pzig, Germany
Citazione:
G.J. Fritz e O. Herbarth, "Pulmonary function and urban air pollution in preschool children", INT J HYG E, 203(3), 2001, pp. 235-244

Abstract

Epidemiologic evidence indicates that respiratory disease in infancy and childhood has respiratory health consequences in later life. Pulmonary function is considered a good index of early effects. This study assessed the relationship of pulmonary function in preschool children in Leipzig, Germany,and exposure to high levels of air pollution during early childhood. Spirometric measures were taken of 235 preschoolers (126 boys, 109 girls, mean age 5.1 +/- 1.3 years) attending 16 randomly selected daycare centres,using the 'Bosch Spiro 501' spirometer. The results showed decrements in the average FVC (85.5 % predicted [pred]) and FEV1 (90.2 % pred) differing with spatial variations in the ambient air pollution burden of the children's residential area. Exposure to a pollution profile of heavy traffic and/ordomestic heating showed markedly lower FVC (78.9 % and 85.5 % pred, respectively) and FEV1 (82.4 % and 88.5 % pred). Miller's Diagnostic Quadrant Model of Disease Classification, categorizing pulmonary function data for preliminary diagnostic purposes, assessed the lung function values (FVC % pred / relative FEV1 [FEV1/FVC] %) of a significant number of children as 'restrictions' (n = 52; 22.1 %). Summarizing: variations in spirometric indices were observed across exposure groups with a significant number of children showing signs of a restrictive ventilatory function. These cross-sectional data, however, do not permit to conclude with any degree of certainty that this is indicative of an early sign of a functional deficit.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 00:48:36