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Titolo:
Variance in treatment compliance and costs by antidepressant class: Analysis in an HMO setting
Autore:
Baker, AM; Russell, JM; Campbell, JK;
Indirizzi:
Pfizer Inc, Outcomes Management Strategies, New York, NY 10017 USA Pfizer Inc New York NY USA 10017 ement Strategies, New York, NY 10017 USA Univ Texas, Med Branch, Dept Psychiat, Galveston, TX 77550 USA Univ TexasGalveston TX USA 77550 Dept Psychiat, Galveston, TX 77550 USA
Titolo Testata:
FORMULARY
fascicolo: 3, volume: 36, anno: 2001,
pagine: 204 - 210
SICI:
1082-801X(200103)36:3<204:VITCAC>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEROTONIN REUPTAKE INHIBITORS; TRICYCLIC ANTIDEPRESSANTS; PRIMARY-CARE; DEPRESSION; FLUOXETINE; SELECTION; METAANALYSIS; EXPENDITURES; CONSTRAINTS; SERTRALINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Baker, AM Pfizer Inc, Outcomes Management Strategies, 235 E 42nd St, New York, NY 10017 USA Pfizer Inc 235 E 42nd St New York NY USA 10017 ork, NY 10017 USA
Citazione:
A.M. Baker et al., "Variance in treatment compliance and costs by antidepressant class: Analysis in an HMO setting", FORMULARY, 36(3), 2001, pp. 204-210

Abstract

We conducted a retrospective analysis of claims data from a large HMO in the southwestern United States to determine whether compliance with the Agency for Health Care Policy and Research (AHCPR) guideline for antidepressanttherapy duration varied by antidepressant class, and how compliance correlated with depression-related, non-depression-related, and total health carecosts. Compliance and treatment costs were evaluated for 12 months following the first antidepressant prescription for all HMO enrollees who were diagnosed with depressive disorder and met inclusion criteria over a 21/2-yearperiod (N = 5,627), Patients who were initially prescribed selective serotonin reuptake inhibitors (SSRIs) were more likely to meet AHCPR treatment duration recommendations (greater than or equal to 150 days of therapy) thanwere patients initially prescribed tricyclic antidepressants (TCAs) or atypical/heterocyclic antidepressants (p < 0,001), Among patients compliant with the AHCPR recommendations, mean total and non-depression-related costs were significantly lower for those prescribed SSRIs than for those prescribed TCAs or atypical/heterocyclic agents. As compliance improved, mean total health care costs remained stable in the SSRI cohort but generally increased in the other two cohorts.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 06:06:24