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Titolo:
Pathophysiological relevance of mitochondria in NAD(+) metabolism
Autore:
Di Lisa, F; Ziegler, M;
Indirizzi:
Univ Padua, Dipartimento Chim Biol, I-35121 Padua, Italy Univ Padua Padua Italy I-35121 artimento Chim Biol, I-35121 Padua, Italy Free Univ Berlin, Inst Biochem, D-14195 Berlin, Germany Free Univ Berlin Berlin Germany D-14195 Biochem, D-14195 Berlin, Germany
Titolo Testata:
FEBS LETTERS
fascicolo: 1-2, volume: 492, anno: 2001,
pagine: 4 - 8
SICI:
0014-5793(20010309)492:1-2<4:PROMIN>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
RAT-LIVER MITOCHONDRIA; CYCLIC ADP-RIBOSE; NICOTINAMIDE-ADENINE-DINUCLEOTIDE; PERMEABILITY TRANSITION PORE; CYCLOSPORINE-A; POLY(ADP-RIBOSE) POLYMERASE; MECHANISTIC ASPECTS; CALCIUM FLUXES; CELL-DEATH; GLYCOHYDROLASE;
Keywords:
permeability transition; myocardial ischemia; cell death; poly(ADP-ribose) polymerase; ADP-ribosylation; cyclic ADP-ribose; oxyradical;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
51
Recensione:
Indirizzi per estratti:
Indirizzo: Di Lisa, F Univ Padua, Dipartimento Chim Biol, Viale Giuseppe Colombo 3, I-35121 Padua, Italy Univ Padua Viale Giuseppe Colombo 3 Padua Italy I-35121 Italy
Citazione:
F. Di Lisa e M. Ziegler, "Pathophysiological relevance of mitochondria in NAD(+) metabolism", FEBS LETTER, 492(1-2), 2001, pp. 4-8

Abstract

Pyridine nucleotides are mostly stored within mitochondria where they are involved in different functions ranging from energy metabolism to cellular signaling. Here we discuss the mechanisms of mitochondrial NAD(+) metabolism and release that mag contribute to the crucial roles played by these organelles as triggers or amplifiers of physiological and pathological events. (C) 2001 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 20:29:42