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Titolo:
Different baseline sympathovagal balance and cardiac autonomic responsiveness in ischemic and non-ischemic congestive heart failure
Autore:
Malfatto, G; Branzi, G; Gritti, S; Sala, L; Bragato, R; Perego, GB; Leonetti, G; Facchini, M;
Indirizzi:
Univ Milan, Ist Sci Osped San Luca, Ist Auxol Italiano, IRCCS,Div Cardiol,Milan, Italy Univ Milan Milan Italy t Auxol Italiano, IRCCS,Div Cardiol,Milan, Italy
Titolo Testata:
EUROPEAN JOURNAL OF HEART FAILURE
fascicolo: 2, volume: 3, anno: 2001,
pagine: 197 - 202
SICI:
1388-9842(200103)3:2<197:DBSBAC>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; RR-INTERVAL VARIABILITY; POWER SPECTRAL-ANALYSIS; SYMPATHETIC PREDOMINANCE; MORTALITY; PROGRESSION; ACTIVATION; MODULATION; METOPROLOL; DISEASE;
Keywords:
autonomic nervous system; sympatho-vagal balance; heart failure; ischemic heart disease; idiopathic dilated cardiomyopathy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Malfatto, G Univ Milan, Ist Sci Osped San Luca, Ist Auxol Italiano, IRCCS,Div Cardiol,Milan, Italy Univ Milan Milan Italy iano, IRCCS,Div Cardiol,Milan, Italy
Citazione:
G. Malfatto et al., "Different baseline sympathovagal balance and cardiac autonomic responsiveness in ischemic and non-ischemic congestive heart failure", EUR J HE FA, 3(2), 2001, pp. 197-202

Abstract

Background: A profound autonomic unbalance is present in heart failure: its correlation with the etiology of the disease has never been investigated. Aims: We characterized the sympatho-vagal balance and autonomic responsiveness of 42 patients (21 with ischemic heart failure, 21 with idiopathic dilated cardiomyopathy). Patients had comparable NYHA class, ejection fraction, exercise pVO(2), exercise ventilatory response, incidence of p-blocking treatment. None showed periodic breathing or nocturnal arterial desaturation. Methods: Heart rate variability was assessed in the time and frequency domain during: (1) 10 min of quiet supine resting and free breathing; (2) 10 min of regular breathing at a frequency of 20 acts/min (= parasympathetic stimulus); and (3) 10 min of active standing (= sympathetic stimulus). The ratio of the low- to high-frequency components of each autospectrum obtainedin the frequency domain (LF/HF) was used as an index of sympathovagal balance. Results: Patients with ischemic heart failure had a greater baseline sympathetic activation (higher LF/HF) than those with idiopathic dilated cardiomyopathy, maintaining some parasympathetic responsiveness as well (reduced LF/HF with regular breathing). Conclusions: There is distinct autonomic control according to the etiology of heart failure, a finding that may helpunderstanding its pathophysiology, and could be useful in the clinical management of patients. (C) 2001 European Society of Cardiology. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 00:19:08