Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Altered baroreflex gain during voluntary breathing in chronic heart failure
Autore:
Mangin, L; Monti, A; Medigue, C; Macquin-Mavier, I; Lopes, ME; Gueret, P; Castaigne, A; Swynghedauw, B; Mansier, P;
Indirizzi:
Hop Henri Mondor, Pharmacol Clin, F-94010 Creteil, France Hop Henri Mondor Creteil France F-94010 ol Clin, F-94010 Creteil, France INRIA Rocquencourt, Le Chesnay, France INRIA Rocquencourt Le Chesnay France A Rocquencourt, Le Chesnay, France Hop Henri Mondor, Fed Cardiol, F-94010 Creteil, France Hop Henri Mondor Creteil France F-94010 Cardiol, F-94010 Creteil, France Hop Lariboisiere, INSERM, U127, F-75475 Paris, France Hop Lariboisiere Paris France F-75475 NSERM, U127, F-75475 Paris, France
Titolo Testata:
EUROPEAN JOURNAL OF HEART FAILURE
fascicolo: 2, volume: 3, anno: 2001,
pagine: 189 - 195
SICI:
1388-9842(200103)3:2<189:ABGDVB>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYMPATHETIC-NERVE ACTIVITY; BLOOD-PRESSURE; SPECTRAL-ANALYSIS; RATE-VARIABILITY; CARDIOVASCULAR-SYSTEM; RR-INTERVAL; HUMANS; SENSITIVITY; NEURONS; ORIGIN;
Keywords:
heart failure; respiration; baroreflex; autonomic nervous system; central nervous system;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Mangin, L Grp Hosp Pitie Salpetriere, Serv Pneumol, Unite Reanimat, 47-83 Blvd Hop, F-75651 Paris, France Grp Hosp Pitie Salpetriere 47-83 Blvd Hop Paris France F-75651
Citazione:
L. Mangin et al., "Altered baroreflex gain during voluntary breathing in chronic heart failure", EUR J HE FA, 3(2), 2001, pp. 189-195

Abstract

Background: We assessed the behavior of the baroreflex (BR) gain in chronic heart failure (CHF) patients using the spectral analysis method during application of a forcing stimulus, i.e. respiration. Methods: Simultaneous RRinterval and arterial pressure fluctuation recordings were obtained duringtwo random-order periods of voluntary paced-breathing (0.15 Hz and 0.25 Hz) in seven patients with moderate CHF (NYHA class II/III; EF, 30 +/- 9%; peak VO2, 18 +/- 5 ml kg(-1) min(-1)) and six age-matched controls. BR gain was assessed in the time (sequential method) and frequency (cross-spectral gain in the low and high frequency) domains. Results: Slower breathing was associated with a BR gain decrease in CHF patients whereas a BR gain increase was evidenced in controls (BR gain: 6 +/- 5 ms mmHg(-1) at 0.25 Hz vs. 4 /- 3 ms mmHg(-1) at 0.15 Hz, P < 0.05 in CHF; BR gain: 12 <plus/minus> 7 ms mmHg(-1) at 0.25 Hz vs. 15 +/- 7 ms mmHg(-1) at 0.15 Hz, P < 0.05 in controls). Conclusions: Voluntary breathing, which involves cortical centers inthe brain, had major effects on cardiovascular system controller gain in CI-IF patients, indicating an impairment of the central neural regulation ofthe autonomic outflow. (C) 2001 European Society of Cardiology. All rightsreserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 15:59:21