Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Trends in cardiogenic shock: report from the SHOCK Study
Autore:
Carnendran, L; Abboud, R; Sleeper, LA; Gurunathan, R; Webb, JG; Menon, V; Dzavik, V; Cocke, T; Hochman, JS;
Indirizzi:
Columbia Univ, St Lukes Roosevelt Hosp Ctr, New York, NY 10025 USA Columbia Univ New York NY USA 10025 velt Hosp Ctr, New York, NY 10025 USA Mt Sinai Med Ctr, New York, NY 10029 USA Mt Sinai Med Ctr New York NY USA10029 ai Med Ctr, New York, NY 10029 USA Univ Alberta Hosp, Edmonton, AB T6G 2B7, Canada Univ Alberta Hosp Edmonton AB Canada T6G 2B7 Edmonton, AB T6G 2B7, Canada Univ British Columbia, St Pauls Hosp, Vancouver, BC V5Z 1M9, Canada Univ British Columbia Vancouver BC Canada V5Z 1M9 ver, BC V5Z 1M9, Canada New England Res Inst, Watertown, MA 02172 USA New England Res Inst Watertown MA USA 02172 Inst, Watertown, MA 02172 USA
Titolo Testata:
EUROPEAN HEART JOURNAL
fascicolo: 6, volume: 22, anno: 2001,
pagine: 472 - 478
SICI:
0195-668X(200103)22:6<472:TICSRF>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; CORONARY HEART-DISEASE; EARLY REVASCULARIZATION; PRIMARY ANGIOPLASTY; TRIAL REGISTRY; GUSTO-I; MORTALITY; THERAPY; COUNTERPULSATION; MANAGEMENT;
Keywords:
myocardial infarction; cardiogenic shock; prognosis; and mortality;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Hochman, JS Columbia Univ, St Lukes Roosevelt Hosp Ctr, 1111 Amsterdam Ave, New York, NY 10025 USA Columbia Univ 1111 Amsterdam Ave New York NY USA 10025 025 USA
Citazione:
L. Carnendran et al., "Trends in cardiogenic shock: report from the SHOCK Study", EUR HEART J, 22(6), 2001, pp. 472-478

Abstract

Aims We analysed time trends in patient characteristics, management, and outcomes of cardiogenic shock complicating acute myocardial infarction in the international, prospective SHOCK Trial Registry and pre-study Registry. Background Despite therapeutic advances in its management, the incidence and high mortality of this complication has remained unchanged for decades. However, in recent years mortality was reported to decrease in one community concomitant with increasing use of revascularization. Methods Thirty-six centres registered 1380 patients with suspected cardiogenic shock complicating acute myocardial infarction from January 1992 to August 1997. Patient and myocardial infarction characteristics, haemodynamics, medications, procedure use, and vital status at discharge were recorded. Results In all, 79% of patients had shock due to predominant pump failure (non-mechanical aetiology). The aetiology, patient profile, and clinical characteristics of cardiogenic shock did not differ over time, except for increases in the incidence of prior bypass surgery (P=0.054) and transfers to tertiary centres (P=0.008). In all, 44% underwent revascularization (n=485), with angioplasty performed more often than bypass surgery (69% vs 31%). The revascularization rate increased over time (P=0.006) with a significant decrease in the time to revascularization (P=0.033). The use of Swan-Ganz catheterization decreased over time (P=0.018), as did the mean length of hospitalization (P=0.034). Overall in-hospital mortality was high (63%) but decreased over time in all patients (P=0.004) and those with pump failure (P=0.018). Mortality was lower for patients who underwent revascularization compared to those who were not revascularized (41% vs 79%, P<0.001). Conclusions Cardiogenic shock complicating acute myocardial infarction is associated with a high mortality rate, but mortality decreased significantly from 1992 to 1997. This partly reflects the greater use of revascularization, which was associated with better outcomes. The reported international trend towards shorter admissions for myocardial infarction was also observed in this cohort. (C)) 2001 The European Society of Cardiology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 03:50:22