Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Bisphosphonate inhibits alveolar bone resorption in experimentally-inducedperi-implantitis in dogs
Autore:
Shibutani, T; Inuduka, A; Horiki, I; Luan, QX; Iwayama, Y;
Indirizzi:
Asahi Univ, Sch Dent, Dept Periodontol, Gifu 50102, Japan Asahi Univ Gifu Japan 50102 ch Dent, Dept Periodontol, Gifu 50102, Japan Beijing Med Univ, Sch Stomatol, Dept Periodontol, Beijing 100083, Peoples R China Beijing Med Univ Beijing Peoples R China 100083 100083, Peoples R China
Titolo Testata:
CLINICAL ORAL IMPLANTS RESEARCH
fascicolo: 2, volume: 12, anno: 2001,
pagine: 109 - 114
SICI:
0905-7161(200104)12:2<109:BIABRI>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXPERIMENTAL PERIODONTITIS; BEAGLE DOGS; MONKEYS;
Keywords:
peri-implantitis; biophosphonate; alveolar bone resorption; dogs; bone marker;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Shibutani, T Asahi Univ, Sch Dent, Dept Periodontol, 1851 Hozumi, Gifu 50102, Japan Asahi Univ 1851 Hozumi Gifu Japan 50102 i, Gifu 50102, Japan
Citazione:
T. Shibutani et al., "Bisphosphonate inhibits alveolar bone resorption in experimentally-inducedperi-implantitis in dogs", CLIN OR IMP, 12(2), 2001, pp. 109-114

Abstract

The purpose of this study was to determine the effect of bisphosphonate onalveolar bone resorption in experimentally-induced peri-implantitis in beagle dogs. Experimental peri-implantitis was induced by ligation around the abutments, 6 months after placement of a fixture. Pamidronate (0.6 mg/kg) was injected intramuscularly every 3 days into each of 5 dogs. Another 5 dogs served as the control group and were injected with saline only. Peripheral blood and urine samples were collected every week up to 12 weeks after placement of the ligature. Standard X-rays were taken every week. Urinary deoxypyridinoline (DPD) and serum osteocalcin (OC) were evaluated by ELISA as markers of alveolar bone remodeling. X-ray films were analyzed with a computer image analyzer. After 12 weeks, the bone level was measured after removal of the gingival flap. The distance between the top surface of the fixture and the fundus of the defect was significantly lower in the Pamidronate group (1.59+/-0.55 mm, mean+/-SD) than in the control group (2.41+/-0.48 mm). Bone density analyzed from the X-ray films was significantly higher in the bisphosphonate group (69.2+/-8.7%, mean+/-SD) than in the control group (50.3+/-12.8%) after 2 to 8 weeks compared with the baseline value (100%). OC and DPD levels fluctuated during the experimental period. These findings suggest that bisphosphonate inhibits the progression of alveolar bone resorption during ligature-induced peri-implantitis in dogs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 13:54:14