Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Tissue Doppler imaging differentiates transmural from nontransmural acute myocardial infarction after reperfusion therapy
Autore:
Derumeaux, G; Loufoua, J; Pontier, G; Cribier, A; Ovize, M;
Indirizzi:
INSERM, E9920, Rouen, France INSERM Rouen FranceINSERM, E9920, Rouen, France Lab Physiol Lyon Nord, Lyon, France Lab Physiol Lyon Nord Lyon FranceLab Physiol Lyon Nord, Lyon, France
Titolo Testata:
CIRCULATION
fascicolo: 4, volume: 103, anno: 2001,
pagine: 589 - 596
SICI:
0009-7322(20010130)103:4<589:TDIDTF>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY REPERFUSION; REGIONAL WALL-MOTION; ISCHEMIC MYOCARDIUM; INTEGRATED BACKSCATTER; STUNNED MYOCARDIUM; ECHOCARDIOGRAPHY; DOG; CONTRACTION; RECOVERY; FLOW;
Keywords:
echocardiography; imaging; myocardial infarction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Derumeaux, G Hop Charles Nicolle, 1 Rue Germont, F-76000 Rouen, France HopCharles Nicolle 1 Rue Germont Rouen France F-76000 rance
Citazione:
G. Derumeaux et al., "Tissue Doppler imaging differentiates transmural from nontransmural acute myocardial infarction after reperfusion therapy", CIRCULATION, 103(4), 2001, pp. 589-596

Abstract

Background-The evaluation of transmural extent of necrosis after acute myocardial infarction remains a major problem in clinical practice. We sought to determine whether color M-mode tissue Doppler imaging (TDI) could differentiate transmural from nontransmural myocardial infarction. Methods and Results-Twenty-one anesthetized open-chest dogs underwent 90 or 120 minutes of left anterior descending coronary artery occlusion followed by 180 minutes of reperfusion, The transmural extension of infarct was measured by triphenyltetrazolium chloride (TTC) staining. Segment shortening in the endocardium and epicardium of the anterior and posterior walls was assessed by sonomicrometry. Regional myocardial blood flow was measured by radioactive microspheres. TDT was obtained from an epicardial short-axis view. We calculated systolic and diastolic velocities within the endocardium and epicardium of myocardial walls and the subsequent myocardial velocity gradient (MVG). TTC staining could identify 2 groups according to the transmural extent of necrosis: 15 dogs had a nontransmural (NT) necrosis (42+/-3% of wall thickness), and 6 dogs developed a transmural (T) infarct (81+/-4% of wall thickness). In both groups, ischemia resulted in a significant and similar reduction in endocardial and epicardial velocities, with a resulting low systolic MVG in the anterior wall (0.10+/-0.07 in NT and 0.10+/-0.08 s(-1) in T). At 60 minutes of reperfusion, systolic MVG failed to change significantly in the transmural group (-0.20+/-0.09 s(-1)). In contrast, it increased significantly after reflow in the NT group compared with ischemic values (-0.99+/-0.20 versus 0.10+/-0.07 s(-1), P<0.05). Conclusions-TDI can differentiate transmural from nontransmural myocardialinfarction early after reperfusion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/10/20 alle ore 02:43:06