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Titolo:
QT dispersion has no prognostic information for patients with advanced congestive heart failure and reduced left ventricular systolic function
Autore:
Brendorp, B; Elming, H; Jun, L; Kober, L; Malik, M; Jensen, GB; Torp-Pedersen, C;
Indirizzi:
Copenhagen Univ Hosp, Dept Cardiol, DK-2900 Hellerup, Denmark Copenhagen Univ Hosp Hellerup Denmark DK-2900 DK-2900 Hellerup, Denmark Univ London St Georges Hosp, Sch Med, London SW17 0RE, England Univ LondonSt Georges Hosp London England SW17 0RE on SW17 0RE, England Copenhagen Univ Hosp, Hvidovre, Denmark Copenhagen Univ Hosp Hvidovre Denmark agen Univ Hosp, Hvidovre, Denmark
Titolo Testata:
CIRCULATION
fascicolo: 6, volume: 103, anno: 2001,
pagine: 831 - 835
SICI:
0009-7322(20010213)103:6<831:QDHNPI>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; IDIOPATHIC DILATED CARDIOMYOPATHY; INTERVAL DISPERSION; ARRHYTHMIC EVENTS; RISK; MARKER; DEATH; DYSFUNCTION; MORTALITY; PREDICTOR;
Keywords:
electrophysiology; heart failure; prognosis; arrhythmia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Brendorp, B Copenhagen Univ Hosp, Dept Cardiol, Post 4210,Niels Andersen Vej 65, DK-2900 Hellerup, Denmark Copenhagen Univ Hosp Post 4210,Niels Andersen Vej 65 Hellerup Denmark DK-2900
Citazione:
B. Brendorp et al., "QT dispersion has no prognostic information for patients with advanced congestive heart failure and reduced left ventricular systolic function", CIRCULATION, 103(6), 2001, pp. 831-835

Abstract

Background-QT dispersion is a potential prognostic marker of tachyarrhythmic events and death, but it is unclear whether this applies to patients with congestive heart failure (CHF). Methods and Results-Of the 1518 patients with advanced CHF and left ventricular dysfunction enrolled in the Danish Investigations of Arrhythmia and Mortality on Dofetilide-CHF (Diamond-CHF) study, a baseline ECG was available in 1319 patients. Of these, QT dispersion could be measured in 703 patients. During a median follow-up of 18 months (minimum 1 year), 285 patients (41%) died. The median QT dispersion was 70 ms (34/155 ms [5%/95% percentiles]), with no difference between survivors and nonsurvivors. Survival analysis revealed no prognostic information derived from QT dispersion regarding all-cause mortality (risk ratio 1.00, 95% CI 1.00 to 1.00; P=0.74), cardiacmortality (risk ratio 1.00, 95% CI 1.00 to 1.01; P=0.55), or cardiac arrhythmic mortality (risk ratio 1.00, 95% CI 0.99 to 1.01; P = 0.38). Conclusions-QT dispersion has no prognostic value regarding all-cause mortality, cardiac mortality, or cardiac arrhythmic mortality fur patients withadvanced CHF and reduced left ventricular systolic function.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 00:15:51