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Titolo:
Comparison of MRI perfusion imaging and single photon emission computed tomography in chronic stroke
Autore:
Barber, PA; Consolo, HK; Yang, Q; Darby, DG; Desmond, PM; Tress, BM; Davis, SM;
Indirizzi:
Royal Melbourne Hosp, Dept Neurol, Parkville, Vic 3050, Australia Royal Melbourne Hosp Parkville Vic Australia 3050 le, Vic 3050, Australia Royal Melbourne Hosp, Dept Nucl Med, Parkville, Vic 3050, Australia Royal Melbourne Hosp Parkville Vic Australia 3050 le, Vic 3050, Australia Royal Melbourne Hosp, Dept Radiol, Parkville, Vic 3050, Australia Royal Melbourne Hosp Parkville Vic Australia 3050 le, Vic 3050, Australia Univ Melbourne, Parkville, Vic 3052, Australia Univ Melbourne Parkville Vic Australia 3052 arkville, Vic 3052, Australia
Titolo Testata:
CEREBROVASCULAR DISEASES
fascicolo: 2, volume: 11, anno: 2001,
pagine: 128 - 136
SICI:
1015-9770(2001)11:2<128:COMPIA>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; HIGH-RESOLUTION MEASUREMENT; DIFFUSION-WEIGHTED MRI; TRACER BOLUS PASSAGES; ACUTE ISCHEMIC STROKE; HYPERACUTE STROKE; VOLUME; AMPHETAMINE; INFARCTION; VALIDATION;
Keywords:
computed tomography; ischemic stroke; magnetic resonance imaging; perfusion; single photon emission computed tomography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Davis, SM Royal Melbourne Hosp, Dept Neurol, Parkville, Vic 3050, Australia Royal Melbourne Hosp Parkville Vic Australia 3050 50, Australia
Citazione:
P.A. Barber et al., "Comparison of MRI perfusion imaging and single photon emission computed tomography in chronic stroke", CEREB DIS, 11(2), 2001, pp. 128-136

Abstract

There have been few direct comparisons between MR perfusion-weighted imaging (PWI) and established perfusion imaging techniques, and none in chronic stroke. We therefore studied 17 chronic hemispheric infarction patients (mean, 90 days) and compared hypoperfusion volumes determined from PWI maps ofrelative cerebral blood flow (rCBF) and volume (rCBV), and mean transit time (rMTT) with those measured with Tc-99-HMPAO single photon emission computed tomography (SPECT). Comparisons were also made between infarct size (T-2- WI) and clinical scales. Correlations were found between lesion locationand volume in all three PWI hemodynamic parameter maps with clinical stateand lesions on SPECT and T-2-WI. In 3 patients, rCBF and rCBV lesions extended well beyond the borders of moderate-sized infarctions, We conclude that in chronic stroke, PWI can delineate regions of abnormal perfusion that reflect the degree of functional impairment and structural damage. The finding of peri-infarct hypoperfusion suggests that PWI may have the potential to provide a rapid and noninvasive template against which interventional strategies aimed at promoting functional recovery may be investigated. Copyright (C) 2001 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 18:57:18