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Titolo:
Absence of circulating microemboli in patients with atrial fibrillation undergoing electric cardioversion
Autore:
Nabavi, DG; Allroggen, A; Reinecke, H; Kemeny, V; Droste, DW; Breithardt, G; Ringelstein, EB;
Indirizzi:
Univ Munster, Dept Neurol, D-4400 Munster, Germany Univ Munster Munster Germany D-4400 Dept Neurol, D-4400 Munster, Germany Univ Munster, Dept Cardiol & Angiol, D-4400 Munster, Germany Univ MunsterMunster Germany D-4400 ol & Angiol, D-4400 Munster, Germany Univ Munster, Atherosclerosis Res Inst, D-4400 Munster, Germany Univ Munster Munster Germany D-4400 is Res Inst, D-4400 Munster, Germany
Titolo Testata:
CEREBROVASCULAR DISEASES
fascicolo: 2, volume: 11, anno: 2001,
pagine: 95 - 99
SICI:
1015-9770(2001)11:2<95:AOCMIP>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTENSITY TRANSIENT SIGNALS; CAROTID-ARTERY STENOSIS; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; TRANSCRANIAL DOPPLER; CEREBRAL MICROEMBOLISM; ASYMPTOMATIC EMBOLIZATION; APPENDAGE FUNCTION; RISK; ANTICOAGULATION; THERAPY;
Keywords:
atrial fibrillation; embolism; ultrasonography, diagnostic; cardioversion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Nabavi, DG Univ Hosp Munster, Dept Neurol, Albert Schweitzer Str 33, D-48129 Munster,Germany Univ Hosp Munster Albert Schweitzer Str 33 Munster Germany D-48129
Citazione:
D.G. Nabavi et al., "Absence of circulating microemboli in patients with atrial fibrillation undergoing electric cardioversion", CEREB DIS, 11(2), 2001, pp. 95-99

Abstract

Electrical cardioversion (CV) of atrial fibrillation (AF) is associated with an increased risk of stroke, and its appropriate prevention is still a matter of debate. It is known that, besides dislodgement of pre-existing intra-atrial thrombi, the 'stunned' atrium after CV is an important cause of thrombus formation and subsequent embolism. We investigated whether CV of AFis associated with occurrence of circulating microemboli (ME) representinga sensitive marker of the actual thromboembolic activity. Twenty-nine patients (22 men) aged 54 +/- 13 years suffering from valvular (n = 5) or nonvalvular (n = 24) AF were studied. All but 1 patient (with recent-onset AF) had been put on oral anticoagulation (INR >2.0) for at least 3 weeks before and 4 weeks after successful CV. In all patients, exclusion of internal carotid artery stenosis and atrial thrombus was performed prior to CV. Five unilateral 1-hour transcranial Doppler ME monitorings over the middle cerebral artery were performed (1) before CV, and (2) immediately, (3) 4-6 h, (4) 24 h, and (5) 2-4 weeks after CV. Total absence of circulating ME was foundbefore CV as well as during a cumulative monitoring time of 115 h after successful CV. Electrical CV of AF after at least 3 weeks of effective anticoagulation is not associated with occurrence of cerebral circulating ME. This finding requires further investigation including high-risk patients with AF undergoing CV based on different treatment protocols. Copyright (C) 2001S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/21 alle ore 08:59:04