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Titolo:
Role of repeated F-18 fluorodeoxyglucose imaging in management of patientswith bone and soft tissue sarcoma
Autore:
El-Zeftawy, H; Heiba, SI; Jana, S; Rosen, G; Salem, S; Santiago, JF; Abdel-Dayem, HM;
Indirizzi:
New York Med Coll, Dept Radiol, Nucl Med Sect, St Vincents Catholic Med Ctr New York, Valhalla, NY 10595 USA New York Med Coll Valhalla NY USA 10595 New York, Valhalla, NY 10595 USA St Vincents Comprehens Canc Ctr, Dept Med, Sect Med Oncol, New York, NY USA St Vincents Comprehens Canc Ctr New York NY USA Oncol, New York, NY USA
Titolo Testata:
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
fascicolo: 1, volume: 16, anno: 2001,
pagine: 37 - 46
SICI:
1084-9785(200102)16:1<37:RORFFI>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON-EMISSION-TOMOGRAPHY; COMPUTED-TOMOGRAPHY; MUSCULOSKELETAL TUMORS; FLUORINE-18-FDG PET;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Abdel-Dayem, HM St Vincents Catholic Med Ctrs New York, 153 W 11 St, New York, NY 10011 USA St Vincents Catholic Med Ctrs New York 153 W 11 St New York NY USA 10011
Citazione:
H. El-Zeftawy et al., "Role of repeated F-18 fluorodeoxyglucose imaging in management of patientswith bone and soft tissue sarcoma", CANC BIO R, 16(1), 2001, pp. 37-46

Abstract

Aim of the study: To assess the impact of repeated F-18 FDG studies on themanagement of patients with bone and soft tissue (B&S) sarcomas. Material and Methods: Twenty patients with B&S tissue tumors (11 M and 9 Fage 17-72 years) had 52 F-18 FDG Dual Head Coincidence Imaging (DHCI) studies. 7 patients were followed for 6 months to 2 years clinically after removal of the primary tumor. Thirteen patients were evaluated for suspected recurrences. Patient's preparation, F-18 FDG injection and imaging procedure were done according to department protocol. Attenuation corrected images were interpreted visually by 3 trained physicians. Tumor to background ratioswere calculated for all lesions. Results: In 13 patients having both studies, baseline FDG and CT/MRI were concordant in 8 patients, FDG defected more lesions in 3 patients but it did not detect 4 metastatic pulmonary nodules in 2 patients. Follow up studies showed stable disease in 10 patients while 6 patients who showed worsening disease needed to change their chemotherapy. Surgery was avoided in 2 patients and 2 patients showed improved response. Conclusion: Repeated F-18 FDG DHCI examinations proved to have an impact on the clinical management of patients with malignant bone and soft tissue sarcoma. It helps to differentiate postoperative changes from local recurrence.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/01/20 alle ore 12:29:43