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Titolo:
Benzodiazepines and hip fractures in elderly people: case-control study
Autore:
Pierfitte, C; Macouillard, G; Thicoipe, M; Chaslerie, A; Pehourcq, F; Aissou, M; Martinez, B; Lagnaoui, R; Fourrier, A; Begaud, B; Dangoumau, J; Moore, N;
Indirizzi:
CHU Bordeaux, Hop Pellegrin, Serv Urgencies, Bordeaux, France CHU Bordeaux Bordeaux France ellegrin, Serv Urgencies, Bordeaux, France CHU Bordeaux, Hop Pellegrin, Serv Urgencies, F-33076 Bordeaux, France CHU Bordeaux Bordeaux France F-33076 Urgencies, F-33076 Bordeaux, France CHU Bordeaux, Dept Pharmacol, Clin Pharmacol Unit, F-33076 Bordeaux, France CHU Bordeaux Bordeaux France F-33076 acol Unit, F-33076 Bordeaux, France CHU Bordeaux, Hop Pellegrin, Dept Anesthesie Reanimat, F-33076 Bordeaux, France CHU Bordeaux Bordeaux France F-33076 Reanimat, F-33076 Bordeaux, France
Titolo Testata:
BRITISH MEDICAL JOURNAL
fascicolo: 7288, volume: 322, anno: 2001,
pagine: 704 - 708
SICI:
0959-535X(20010324)322:7288<704:BAHFIE>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
NURSING-HOME RESIDENTS; ELIMINATION HALF-LIFE; RISK-FACTORS; COGNITIVE IMPAIRMENT; THIAZIDE DIURETICS; FALLS; COMMUNITY; ANTIDEPRESSANTS; DEMENTIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Moore, N Victor Segalen Univ, Dept Pharmacol, F-33076 Bordeaux, France Victor Segalen Univ Bordeaux France F-33076 76 Bordeaux, France
Citazione:
C. Pierfitte et al., "Benzodiazepines and hip fractures in elderly people: case-control study", BR MED J, 322(7288), 2001, pp. 704-708

Abstract

Objective To determine whether benzodiazepines are associated with an increased risk of hip facture. Design Case-control study. Participants All incident cases of hip fracture not related to traffic accidents or cancer in patients ol er 65 years of age. 245 cases were matched to 817 controls. Setting Emergency department of a university hospital. Main outcome measures Exposure to benzodiazepines and other potential riskol protective factors or lifestyle items. Results The use of benzodiazepines as determined from questionnaires, medical records, or plasma samples at admission to hospital was not associated with an increased risk of hip fracture (odds ratio 0.9, 95% confidence interval 0.5 to 1.5). Hip fracture was, however, associated with the use of twoof more benzodiazepines, as determined from questionnaires or medical records but not from plasma samples. Of the individual drugs, only lorazepam was significantly associated with an increased risk of hip fracture (1.8, 1.1to 3.1). Conclusion Except for lorazepam, the presence of benzodiazepines in plasmawas not associated with an increased risk of hip fracture. nle method usedto ascertain exposure could influence the results of case-control studies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 16:30:59