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Titolo:
Synthesis of metabolically blocked paclitaxel analogues
Autore:
Wittman, MD; Altstadt, TJ; Fairchild, C; Hansel, S; Johnston, K; Kadow, JF; Long, BH; Rose, WC; Vyas, DM; Wu, MJ; Zoeckler, ME;
Indirizzi:
Bristol Myers Squibb Co, Pharmaceut Res Inst, Discovery Chem, Wallingford,CT 06492 USA Bristol Myers Squibb Co Wallingford CT USA 06492 Wallingford,CT 06492 USA Bristol Myers Squibb Co, Pharmaceut Res Inst, Oncol Drug Discovery, Princeton, NJ 08543 USA Bristol Myers Squibb Co Princeton NJ USA 08543 y, Princeton, NJ 08543 USA Bristol Myers Squibb Co, Pharmaceut Res Inst, Dept Metab & Pharmacokinet, Wallingford, CT 06492 USA Bristol Myers Squibb Co Wallingford CT USA 06492allingford, CT 06492 USA
Titolo Testata:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
fascicolo: 6, volume: 11, anno: 2001,
pagine: 809 - 810
SICI:
0960-894X(20010326)11:6<809:SOMBPA>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
BIOLOGICAL-ACTIVITY; TAXOL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Wittman, MD Bristol Myers Squibb Co, Pharmaceut Res Inst, Discovery Chem, POB 5100, Wallingford, CT 06492 USA Bristol Myers Squibb Co POB 5100 Wallingford CT USA 06492 USA
Citazione:
M.D. Wittman et al., "Synthesis of metabolically blocked paclitaxel analogues", BIOORG MED, 11(6), 2001, pp. 809-810

Abstract

The stereospecific syntheses of the metabolically blocked 6-alpha -F, Cl, Br paclitaxel, and 6-alpha -F-10-acetyldocetaxel are described and in vitroand in vivo activity is presented. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 19:15:18