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Titolo:
Colonic intra-epithelial carcinoma occurring in a hyperplastic polyp via aserrated adenoma
Autore:
Tanaka, M; Kusumi, T; Sasaki, Y; Yamagata, K; Ichinohe, H; Nishida, J; Kudo, H;
Indirizzi:
Hirosaki Univ, Sch Med, Dept Pathol, Hirosaki, Aomori 0368562, Japan Hirosaki Univ Hirosaki Aomori Japan 0368562 rosaki, Aomori 0368562, Japan Hirosaki Univ, Sch Med, Dept Internal Med 1, Hirosaki, Aomori 0368562, Japan Hirosaki Univ Hirosaki Aomori Japan 0368562 rosaki, Aomori 0368562, Japan
Titolo Testata:
PATHOLOGY INTERNATIONAL
fascicolo: 3, volume: 51, anno: 2001,
pagine: 215 - 220
SICI:
1320-5463(200103)51:3<215:CICOIA>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
LARGE-INTESTINE; METAPLASTIC POLYP; GASTRIC DIFFERENTIATION; COLORECTAL-CARCINOMA; LARGE BOWEL; ADENOCARCINOMA; CANCER; FEATURES; NECROPSY; RECTUM;
Keywords:
adenocarcinoma; colon and rectum; hyperplastic polyp; serrated adenoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Tanaka, M Hirosaki Univ, Sch Med, Dept Pathol, 5 Zaifu Cho, Hirosaki, Aomori 0368562, Japan Hirosaki Univ 5 Zaifu Cho Hirosaki Aomori Japan 0368562 2, Japan
Citazione:
M. Tanaka et al., "Colonic intra-epithelial carcinoma occurring in a hyperplastic polyp via aserrated adenoma", PATHOL INT, 51(3), 2001, pp. 215-220

Abstract

We present a case of intra-epithelial carcinoma occurring in a serrated adenoma of the colon. The pedunculated polyp, which measured 12 x 10 x 6 mm, was endoscopically removed from the ascending colon of a 78-year-old woman. Histologically, the polyp mainly consisted of serrated adenomatous glands,and had foci of intra-epithelial carcinoma at the top. Hyperplastic (metaplastic) areas were also present in both borders between the serrated adenomatous area and the surrounding normal mucosa. A sequential increase in the degree of dysplasia, and in the number of nuclei positively reactive for Ki-67 and p53 was evident from the hyperplastic areas toward the foci of carcinoma. The polyp described here may represent a carcinogenic potential of hyperplastic polyp via serrated adenoma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 19:28:46