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Titolo:
Magnetic coupling between water and creatine protons in human brain and skeletal muscle, as measured using inversion transfer H-1-MRS
Autore:
Kruiskamp, MJ; de Graaf, RA; van der Grond, J; Lamerichs, R; Nicolay, K;
Indirizzi:
Univ Utrecht, Med Ctr, Dept Expt In Vivo NMR, Image Sci Inst, NL-3584 CJ Utrecht, Netherlands Univ Utrecht Utrecht Netherlands NL-3584 CJ 3584 CJ Utrecht, Netherlands Univ Utrecht, Med Ctr, Dept Radiol, Image Sci Inst, NL-3584 CJ Utrecht, Netherlands Univ Utrecht Utrecht Netherlands NL-3584 CJ 3584 CJ Utrecht, Netherlands Philips Med Syst, Best, Netherlands Philips Med Syst Best NetherlandsPhilips Med Syst, Best, Netherlands
Titolo Testata:
NMR IN BIOMEDICINE
fascicolo: 1, volume: 14, anno: 2001,
pagine: 1 - 4
SICI:
0952-3480(200102)14:1<1:MCBWAC>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
IN-VIVO; RAT-BRAIN; NMR-SPECTROSCOPY; SIGNALS; QUANTIFICATION; INVIVO; MRS;
Keywords:
creatine; phosphocreatine; inversion transfer; human; brain; skeletal muscle;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Nicolay, K Univ Utrecht, Med Ctr, Dept Expt In Vivo NMR, Image Sci Inst, Bolognalaan 50, NL-3584 CJ Utrecht, Netherlands Univ Utrecht Bolognalaan 50 Utrecht Netherlands NL-3584 CJ nds
Citazione:
M.J. Kruiskamp et al., "Magnetic coupling between water and creatine protons in human brain and skeletal muscle, as measured using inversion transfer H-1-MRS", NMR BIOMED, 14(1), 2001, pp. 1-4

Abstract

Using the inversion transfer technique, the possible magnetic coupling between water protons and the protons of low-molecular weight metabolites was investigated in human brain and skeletal muscle at 1.5 T. The localized H-1-MR spectra were recorded at different times after selective inversion of the water resonance. Water inversion led to a significant transient reduction in the signal intensity of the methyl protons of creatine/phosphocreatine, in both tissues. This is indicative of magnetic coupling between the protons of water and those of creatine/phosphocreatine. Neither the choline andN-acetylaspartate protons in brain nor the protons of the trimethylammonium pool in skeletal muscle showed a significant magnetic coupling to mobile water. Copyright (C) 2001 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/08/20 alle ore 00:34:48