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Titolo:
Propagation of rat parvovirus in thymic lymphoma cell line C58(NT)D and subsequent appearance of a resistant cell clone after lytic infection
Autore:
Ueno, Y; Harada, T; Iseki, H; Ohshima, T; Sugiyama, F; Yagami, KI;
Indirizzi:
Univ Tsukuba, Lab Anim Res Ctr, Tsukuba, Ibaraki 3058575, Japan Univ Tsukuba Tsukuba Ibaraki Japan 3058575 sukuba, Ibaraki 3058575, Japan Univ Tsukuba, Inst Basic Med Sci, Tsukuba, Ibaraki 3058575, Japan Univ Tsukuba Tsukuba Ibaraki Japan 3058575 sukuba, Ibaraki 3058575, Japan
Titolo Testata:
JOURNAL OF VIROLOGY
fascicolo: 8, volume: 75, anno: 2001,
pagine: 3965 - 3970
SICI:
0022-538X(200104)75:8<3965:PORPIT>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
ORPHAN PARVOVIRUS; IN-VIVO; NONSTRUCTURAL PROTEINS; APOPTOSIS; H-1; LYMPHOCYTES; INDUCTION; VIRUS; DEATH; VITRO;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Yagami, KI Univ Tsukuba, Lab Anim Res Ctr, 1-1-1 Tennodai, Tsukuba, Ibaraki 3058575, Japan Univ Tsukuba 1-1-1 Tennodai Tsukuba Ibaraki Japan 3058575 Japan
Citazione:
Y. Ueno et al., "Propagation of rat parvovirus in thymic lymphoma cell line C58(NT)D and subsequent appearance of a resistant cell clone after lytic infection", J VIROLOGY, 75(8), 2001, pp. 3965-3970

Abstract

Rat parvovirus (RPV) is nonpathogenic in rats but causes persistent lymphocytotropic infection. We found that RPV was propagated in rat thymic lymphoma cell line C58(NT)D and induced apoptosis. Interestingly, a resistant subclone, C58(NT)D/R, from surviving cells after lytic infection had differentiated phenotypic modifications, such as increased cell adherence, resistance to apoptosis, and suppressed tumorigenicity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 08:55:09