Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Quantifying pulmonary hypertension in ventilated infants with bronchiolitis: A pilot study
Autore:
Fitzgerald, D; Davis, GM; Rohlicek, C; Gottesman, R;
Indirizzi:
Montreal Childrens Hosp, Res Inst, Dept Resp Med, Montreal, PQ H3H 1P3, Canada Montreal Childrens Hosp Montreal PQ Canada H3H 1P3 al, PQ H3H 1P3, Canada Montreal Childrens Hosp, Res Inst, Dept Cardiol, Montreal, PQ H3H 1P3, Canada Montreal Childrens Hosp Montreal PQ Canada H3H 1P3 al, PQ H3H 1P3, Canada Montreal Childrens Hosp, Res Inst, Dept Paediat Intens Care, Montreal, PQ H3H 1P3, Canada Montreal Childrens Hosp Montreal PQ Canada H3H 1P3 al, PQ H3H 1P3, Canada Childrens Hosp, Childrens Chest Res Ctr, Sydney, NSW, Australia Childrens Hosp Sydney NSW Australia hest Res Ctr, Sydney, NSW, Australia
Titolo Testata:
JOURNAL OF PAEDIATRICS AND CHILD HEALTH
fascicolo: 1, volume: 37, anno: 2001,
pagine: 64 - 66
SICI:
1034-4810(200102)37:1<64:QPHIVI>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEONATAL LUNG-DISEASE; NITRIC-OXIDE;
Keywords:
bronchiolitis; pulmonary hypertension; respiratory syncytial virus;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Fitzgerald, D New Childrens Hosp, Dept Resp Med, POB 3515, Parramatta, NSW2124, Australia New Childrens Hosp POB 3515 Parramatta NSW Australia 2124 ia
Citazione:
D. Fitzgerald et al., "Quantifying pulmonary hypertension in ventilated infants with bronchiolitis: A pilot study", J PAEDIAT C, 37(1), 2001, pp. 64-66

Abstract

Objective: To determine whether previously well infants ventilated for bronchiolitis have sufficiently elevated pulmonary artery pressures (PAP) to warrant a trial of inhaled nitric oxide (iNO) therapy. Methods: Consecutive infants mechanically ventilated for bronchiolitis were offered Doppler echocardiography between 24 and 72 h after intubation. Patients were divided into those with normal PAP, mild, moderate or severe pulmonary hypertension. Patients with at least moderate pulmonary hypertension (systolic PAP > 30 mmHg and > 50% of systemic systolic arterial pressure)were offered a 60 min trial of iNO therapy at a concentration of 20 ppm and repeat echocardiography. Results: Six infants (four preterm, two term) were studied at a mean corrected age of 13 weeks (4, 24). Respiratory syncytial virus was confirmed on immunofluorescence of nasal secretions in five of six subjects (84%). Echocardiography was performed (mean, 5.5 days) (95%CI3.8-7.3) after the onset of symptoms. All patients had structurally normal hearts. Four patients had mild pulmonary artery hypertension and two had normal pulmonary artery pressures. None of the patients qualified for iNO therapy. The mean (range) duration of intubation was 14 days (9-19) and the duration of hospitalization was 28 days (14-42). All patients recovered. Conclusion: Significant pulmonary hypertension should not be presumed in previously well preterm and term infants ventilated for bronchiolitis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 23:06:34