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Titolo:
Long-term evaluation of extracorporeal shock-wave lithotripsy for cholesterol gallstones
Autore:
Tsumita, R; Sugiura, N; Abe, A; Ebara, M; Saisho, H; Tsuchiya, Y;
Indirizzi:
Chiba Univ, Sch Med, Dept Med 1, Chuo Ku, Chiba 2608670, Japan Chiba UnivChiba Japan 2608670 Dept Med 1, Chuo Ku, Chiba 2608670, Japan Natl Hlth Insurance Ohami Hosp, Chiba, Japan Natl Hlth Insurance Ohami Hosp Chiba Japan nce Ohami Hosp, Chiba, Japan
Titolo Testata:
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
fascicolo: 1, volume: 16, anno: 2001,
pagine: 93 - 99
SICI:
0815-9319(200101)16:1<93:LEOESL>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
URSODEOXYCHOLIC ACID THERAPY; GALLBLADDER STONES; BILIARY PAIN; RECURRENCE;
Keywords:
biliary symptoms; extracorporeal shock-wave lithotripsy; gallstones; stone recurrence;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Tsumita, R Chiba Univ, Sch Med, Dept Med 1, Chuo Ku, 1-8-1 Inohana, Chiba 2608670, Japan Chiba Univ 1-8-1 Inohana Chiba Japan 2608670 ba 2608670, Japan
Citazione:
R. Tsumita et al., "Long-term evaluation of extracorporeal shock-wave lithotripsy for cholesterol gallstones", J GASTR HEP, 16(1), 2001, pp. 93-99

Abstract

Background: Extracorporeal shock-wave lithotripsy (ESWL) is a treatment that preserves the gallbladder. Problems after ESWL treatment include stone recurrence and the development of biliary symptoms. Methods: Two hundred and sixty-two patients with cholesterol-type gallstones, the best indication for ESWL treatment, and 42 control patients with cholesterol-type gallstones who received no treatment entered this study. We evaluated the factors associated with recurrence of gallstones after stone clearance and the development of biliary symptoms after ESWL treatment. Results: The 3-, 5- and 7-year cumulative probabilities of gallstone recurrence were 20.6, 27.1 and 33.1%, respectively, with the recurrence probability significantly lower in patients with good gallbladder contractility. Inpatients with recurrence, ursodeoxycholic acid (UDCA) treatment was effective. In 69 patients with residual gallstones, the 3-, 5- and 7-year cumulative risks of biliary symptoms were 17.3, 24.9 and 30.5%, respectively. Withresidual gallstones, the risk of biliary symptoms developing was significantly lower in patients with a less than or equal to 3 mm fragment size at the end of ESWL treatment and in those treated consistently with UDCA for 6 months or more after treatment with ESWL. The risk of biliary symptoms was significantly lower in ESWL-treated patients with residual stones who had aless than or equal to 3 mm fragment size after treatment compared to thoseof control patients. Conclusions: Ursodeoxycholic acid was effective in clearing stones in patients with gallstone recurrence. In patients with residual stones, the fragmentation of stones to less than or equal to 3 mm and UDCA administration effectively reduced the risk of subsequent biliary symptoms. (C) 2001 Blackwell Science Asia Pry Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 06:06:07