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Titolo:
Exposure of human oocytes to endometrioma fluid does not alter fertilization or early embryo development
Autore:
Khamsi, F; Yavas, Y; Lacanna, IC; Roberge, S; Endman, M; Wong, JC;
Indirizzi:
Toronto Fertil Steril Inst, Toronto, ON M5R 3N8, Canada Toronto Fertil Steril Inst Toronto ON Canada M5R 3N8 , ON M5R 3N8, Canada
Titolo Testata:
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
fascicolo: 2, volume: 18, anno: 2001,
pagine: 106 - 109
SICI:
1058-0468(200102)18:2<106:EOHOTE>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Keywords:
embryo; endometrioma; fertilization; in vitro fertilization; oocyte; endometriosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
6
Recensione:
Indirizzi per estratti:
Indirizzo: Khamsi, F Toronto Fertil Steril Inst, 66 Ave Rd, Toronto, ON M5R 3N8, Canada Toronto Fertil Steril Inst 66 Ave Rd Toronto ON Canada M5R 3N8 a
Citazione:
F. Khamsi et al., "Exposure of human oocytes to endometrioma fluid does not alter fertilization or early embryo development", J AS REPROD, 18(2), 2001, pp. 106-109

Abstract

Background: Extensive endometriosis causes a mechanical disturbance in thepelvis leading to obstrcutive-type infertility. However, minimal or mild endometriosis is suspected to cause infertility, possibly through a humoral agent. Previous studies reported the presence of a factor in the serum of patients with endometriosis which reduced fertilization and early embryo formation in a IVF model. Methods: In the present article we report a comparison of oocytes exposed to endometrioma fluid and oocytes not exposed (controls) in the context of a human IVF setting. We have been in the practice of aspirating oocytes into prewarmed 60-ml syringes containing culture medium. We have shown previously that this technique reduces the length of oocyte retrieval without compromising success. In 14 women undergoing oocyte retrieval, we inadvertentlyentered an endometrioma. This resulted in retrieved oocytes that were either exposed or not exposed to endometrioma fluid. Results: In contrast to previous reports, we found no difference in fertilization or early embryo development between the two groups. The fertilization rate for oocytes exposed to an endometrioma was 60%, versus 56% for controls. The good-quality embryo formation rate for oocytes exposed to an endometrioma was 45%, versus 46% for controls.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 06:37:45