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Titolo:
Combined revascularization strategy for acute myocardial infarction in patients with intracoronary thrombus - Preceding intracoronary thrombolysis and subsequent mechanical angioplasty
Autore:
Ishibashi, F; Saito, T; Hokimoto, S; Noda, K; Moriyama, Y; Oshima, S;
Indirizzi:
Kumamoto Cent Hosp, Div Cardiovasc, Kumamoto 8620965, Japan Kumamoto Cent Hosp Kumamoto Japan 8620965 ovasc, Kumamoto 8620965, Japan
Titolo Testata:
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION
fascicolo: 4, volume: 65, anno: 2001,
pagine: 251 - 256
SICI:
0047-1828(200104)65:4<251:CRSFAM>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSLUMINAL CORONARY ANGIOPLASTY; NO-REFLOW PHENOMENON; INTRAVENOUS STREPTOKINASE; RANDOMIZED TRIAL; IMMEDIATE ANGIOPLASTY; BALLOON ANGIOPLASTY; PATHO-PHYSIOLOGY; FERRET HEARTS; FOLLOW-UP; UROKINASE;
Keywords:
acute myocardial infarction; combined therapy; intracoronary thrombus;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Saito, T Kumamoto Cent Hosp, Div Cardiovasc, 96 Tainoshima,Tamukaemachi, Kumamoto 8620965, Japan Kumamoto Cent Hosp 96 Tainoshima,Tamukaemachi Kumamoto Japan 8620965
Citazione:
F. Ishibashi et al., "Combined revascularization strategy for acute myocardial infarction in patients with intracoronary thrombus - Preceding intracoronary thrombolysis and subsequent mechanical angioplasty", JPN CIRC J, 65(4), 2001, pp. 251-256

Abstract

Thrombus in the infarct-related artery is one of the limitations for Row restoration in primary percutaneous trans luminal coronary angioplasty (PTCA) treatment for acute myocardial infarction (AMI). The present study investigated the benefit of preceding intracoronary thrombolysis (ICT) by retrospectively analyzing acute phase flow restoration in 80 AMI patients with intracoronary thrombus: 40 undergoing primary PTCA alone (primary PTCA group) and 40 treated with preceding ICT plus PTCA (combined group). Acute phase Thrombolysis in Myocardial infarction (TIMI) grade flow was as follows: TIMI0/1: 35.0% vs 12.5% for the primary PTCA group and the combined group, p=0.06; TIMI 2: 7.5% vs 15.0%, p=NS; TIMI 3: 57.5% vs 72.5%, p=NS). In the subgroup analysis, it was also less in the combined group among 33 patients with a left anterior descending coronary artery (LAD) lesion (42.1% vs 7.1%, p=0.08), but not among the remaining 47 with either a right coronary artery or left circumflex artery lesion. The combined therapy may potentially provide better acute phase flow restoration in AMI patients with an intracoronary thrombus in a LAD lesion.

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Documento generato il 05/04/20 alle ore 03:33:21