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Titolo:
Thyrotropin-releasing hormone and its receptor in glia
Autore:
Fernandez-Agullo, T;
Indirizzi:
Univ Alcala de Henares, Fac Med, Dept Fisiol, Madrid 28871, Spain Univ Alcala de Henares Madrid Spain 28871 pt Fisiol, Madrid 28871, Spain
Titolo Testata:
GLIA
fascicolo: 4, volume: 33, anno: 2001,
pagine: 267 - 276
SICI:
0894-1491(20010315)33:4<267:THAIRI>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
RAT SPINAL-CORD; GENE-EXPRESSION; MESSENGER-RNA; DORSAL HORN; OPTIC-NERVE; BRAIN-STEM; TRH; CELLS; ASTROCYTES; EXCITABILITY;
Keywords:
TRH; receptor; astroglia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
56
Recensione:
Indirizzi per estratti:
Indirizzo: Fernandez-Agullo, T Univ Alcala de Henares, Fac Med, Dept Fisiol, Carretera Barcelona Km 33, Madrid 28871, Spain Univ Alcala de Henares Carretera Barcelona Km 33 Madrid Spain 28871
Citazione:
T. Fernandez-Agullo, "Thyrotropin-releasing hormone and its receptor in glia", GLIA, 33(4), 2001, pp. 267-276

Abstract

The presence of thyrotropin-releasing hormone (Thyroliberin, TRH) and its receptor (TRH-R) in frozen coronal sections of the adult rat spinal cord and neonatal rat astroglial cultures was investigated by means of immunocytochemistry and Western blot using polyclonal antibodies generated against thehormone and monoclonal antibodies originated against discrete sequences ofthe type 1 rat TRH receptor (TRH-R1). TRH-R1 and TRH are present both in astroglial cells from adult rats and in cultured cells from newborn animals. The localization of TRH and TRH-RI in nonneuronal cells in the central nervous system may reflect that some of the neurotrophic actions of TRH upon the central nervous system are mediated by glial cells. GLIA 33:267-276, 2001. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/05/20 alle ore 04:28:43