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Titolo:
Parametric oesophageal multiple swallow scintigraphy for validation of dysphageal symptoms during external beam irradiation of mediastinal tumours
Autore:
Brandt-Mainz, K; von Mallek, D; Pottgen, C; Eising, EG; Bockisch, A; Stuschke, M; Sack, H;
Indirizzi:
Univ Essen Gesamthsch Klinikum, Klin & Poliklin Nukl Med, D-45122 Essen, Germany Univ Essen Gesamthsch Klinikum Essen Germany D-45122 5122 Essen, Germany Univ Essen Gesamthsch Klinikum, Klin & Poliklin Strahlentherapie, Essen, Germany Univ Essen Gesamthsch Klinikum Essen Germany entherapie, Essen, Germany
Titolo Testata:
EUROPEAN JOURNAL OF NUCLEAR MEDICINE
fascicolo: 3, volume: 28, anno: 2001,
pagine: 313 - 319
SICI:
0340-6997(200103)28:3<313:POMSSF>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
ESOPHAGEAL TRANSIT; RADIATION; REPRODUCIBILITY; LIQUID;
Keywords:
oesophageal multiple swallow scintigraphy parametric condensed images; mediastinal tumours; dysphagia; external beam irradiation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Brandt-Mainz, K Univ Essen Gesamthsch Klinikum, Klin & Poliklin Nukl Med, Hufelandstr 55, D-45122 Essen, Germany Univ Essen Gesamthsch Klinikum Hufelandstr 55 Essen Germany D-45122
Citazione:
K. Brandt-Mainz et al., "Parametric oesophageal multiple swallow scintigraphy for validation of dysphageal symptoms during external beam irradiation of mediastinal tumours", EUR J NUCL, 28(3), 2001, pp. 313-319

Abstract

The aim of the study was to evaluate dysphageal symptoms and to measure the effect of local analgesic treatment using parametric oesophageal multipleswallow scintigraphy (PES) during external beam irradiation of the mediastinal region. Fifteen patients (most with lung cancer) with dysphagia grade II underwent PES during external beam radiotherapy of the mediastinum before and after application of local analgesics. Dynamic parametric condensed images were recorded. The intensity of clinical symptoms was correlated withthe emptying rate at 10 s (ER-10 s) and the mean transit time (MTT). Visual analysis of the images was performed and the results were correlated withthe fields of irradiation portals. Of the 15 patients, 12 showed a correlation between irradiation portals and the region of oesophageal motility disorder. Concordant results of clinical symptoms and PES data were found. In nine patients with a decrease in dysphagia following local analgesia, an increase in mean ER-10 s and a decrease in MTT were observed. In three patients with deterioration in clinical symptoms after analgesic treatment, a similar decrease in mean ER-10 s was found, though MTT remained constant. In three patients with normal values, motility disorders were detected in the dynamic study. In conclusion, PES was found to be a sensitive tool for the validation of dysphageal symptoms in patients during external beam irradiation of mediastinal tumours and for the evaluation and quantification of the efficacy of local analgesic treatment. Additional visual analysis of the dynamic study is helpful in diagnosing minimal disorders.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 17:21:26