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Titolo:
Optimising treatment for resectable rectal cancer - Is preoperative therapy beneficial?
Autore:
Ngan, SYK;
Indirizzi:
Peter MacCallum Canc Inst, Melbourne, Vic, Australia Peter MacCallum Canc Inst Melbourne Vic Australia bourne, Vic, Australia
Titolo Testata:
DRUGS & AGING
fascicolo: 2, volume: 18, anno: 2001,
pagine: 79 - 85
SICI:
1170-229X(2001)18:2<79:OTFRRC>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
RADIATION-THERAPY; RANDOMIZED TRIAL; ADJUVANT THERAPY; CURATIVE SURGERY; RADIOTHERAPY; CARCINOMA; CHEMOTHERAPY; 5-FLUOROURACIL; IRRADIATION; RECURRENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Ngan, SYK Peter MacCallum Canc Inst, Div Radiat Oncol, St Andrews Pl, E Melbourne, Vic 3002, Australia Peter MacCallum Canc Inst St Andrews Pl E Melbourne Vic Australia 3002
Citazione:
S.Y.K. Ngan, "Optimising treatment for resectable rectal cancer - Is preoperative therapy beneficial?", DRUG AGING, 18(2), 2001, pp. 79-85

Abstract

Preoperative radiotherapy is becoming the standard of care for resectable locally advanced adenocarcinoma of the rectum. Its practice is no longer limited to a few specialised cancer centres. Adjuvant preoperative radiotherapy can reduce the risk of local recurrence by 50% compared with surgery alone and it has a moderate effect in improving survival. Treatment-related toxicity is superior to that after postoperative radiotherapy. Early results of preoperative radiotherapy with concurrent chemotherapy are promising, with a low toxicity profile and a high pathological response rate. Advances in technology, endorectal ultrasound and magnetic resonance imaging enable selection of appropriate patients for preoperative radiotherapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/05/20 alle ore 15:09:28