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Titolo:
Acute renal failure in a renal transplant donor due to primary antiphospholipid syndrome
Autore:
Chitalia, VC; Kolhe, N; Kothari, J; Almeida, AF;
Indirizzi:
Univ Bombay, Seth GS Med Coll & KEM Hosp, Dept Med, Div Nephrol, Bombay, Maharashtra, India Univ Bombay Bombay Maharashtra India Nephrol, Bombay, Maharashtra, India
Titolo Testata:
AMERICAN JOURNAL OF NEPHROLOGY
fascicolo: 1, volume: 21, anno: 2001,
pagine: 55 - 57
SICI:
0250-8095(200101/02)21:1<55:ARFIAR>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
CLINICOPATHOLOGICAL CORRELATIONS; ANTIBODY SYNDROME; THROMBOSIS;
Keywords:
antiphospholipid antibody; kidney donor; renal artery thrombosis; streptokinase; primary antiphospholipid syndrome;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Chitalia, VC St Vincents Med Ctr, Dept Med, Bridgeport, CT 06606 USA St Vincents Med Ctr Bridgeport CT USA 06606 rt, CT 06606 USA
Citazione:
V.C. Chitalia et al., "Acute renal failure in a renal transplant donor due to primary antiphospholipid syndrome", AM J NEPHR, 21(1), 2001, pp. 55-57

Abstract

Primary antiphospholipid antibody (APA) syndrome, a common prothrombotic disorder, has been known in dialysis patients and renal transplant recipients. We report a case of primary APA syndrome presenting as a posttransplant complication in a renal transplant donor. A renal donor presented with acute, painless anuria due to renal artery thrombosis 6 years following renal transplant surgery, subsequent thrombosis of jugular catheter and arteriovenous fistula occurred, despite anticoagulation treatment, due to primary APAsyndrome. This incident represents the most catastrophic complication reported in a renal donor due to primary APA syndrome. The validity of a prothrombotic assay in an organ donor workup to detect predilection to hypercoagulable disorders and to prevent such complications is open to question. The actual significance of APA in the blood is unclear; hence, the presence of APA in a potential renal donor would pose an ethical and practical dilemma. Copyright (C) 2001 S. Karger AG, Baser.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 22:55:45