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Titolo:
SV40 and the pathogenesis of mesothelioma
Autore:
Rizzo, P; Bocchetta, M; Powers, A; Foddis, R; Stekala, E; Pass, HI; Carbone, M;
Indirizzi:
Loyola Univ, Dept Pathol, Cardinal Bernardin Canc Ctr, Canc Immunol Program, Maywood, IL 60153 USA Loyola Univ Maywood IL USA 60153 c Immunol Program, Maywood, IL 60153 USA Wayne State Univ, Karmanos Canc Ctr, Aerodigest Program, Detroit, MI 48201USA Wayne State Univ Detroit MI USA 48201 igest Program, Detroit, MI 48201USA
Titolo Testata:
SEMINARS IN CANCER BIOLOGY
fascicolo: 1, volume: 11, anno: 2001,
pagine: 63 - 71
SICI:
1044-579X(200102)11:1<63:SATPOM>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
MALIGNANT PLEURAL MESOTHELIOMA; DNA-SEQUENCES; T-ANTIGEN; SIMIAN-VIRUS-40; VIRUS; INFECTIONS; EXPRESSION; DISEASE; CELLS;
Keywords:
SV40; mesothelioma; asbestos;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Carbone, M Loyola Univ, Dept Pathol, Cardinal Bernardin Canc Ctr, Canc Immunol Program, 2160 S 1st Ave, Maywood, IL 60153 USA Loyola Univ 2160 S 1st Ave Maywood IL USA 60153 d, IL 60153 USA
Citazione:
P. Rizzo et al., "SV40 and the pathogenesis of mesothelioma", SEM CANC B, 11(1), 2001, pp. 63-71

Abstract

Malignant mesothelioma, a tumor of the pleura, pericardium, and peritoneum, is presently a worldwide problem. Current therapy is ineffective in slowing the course of the disease, and median survival from the time of diagnosis is rarely greater than 1 year: While the tumor was almost unknown prior to the second half of the twentieth century, it is presently responsible formore than 2000 deaths per year in the US alone. Mesothelioma is frequentlyassociated with exposure to asbestos, but the incidence of cases involvingindividuals with low, levels of asbestos exposure is increasing. For this reason. there has been much interest in studying whether there are alternative factors that act alone or in conjunction with asbestos in producing this malignancy. In the last decade, simian virus 40 (SV40) has become the most notable suspected agent.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 12:29:08