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Titolo:
Prophylactic cranial irradiation in limited disease small-cell lung cancerin complete remission: a retrospective analysis
Autore:
van der Linden, YM; van Kempen, ML; van der Tweel, I; Vanderschueren, RGJRA; Schlosser, JJ; Lammers, JWJ; Struikmans, H;
Indirizzi:
Univ Med Ctr, Dept Radiotherapy, NL-3584 CX Utrecht, Netherlands Univ Med Ctr Utrecht Netherlands NL-3584 CX 3584 CX Utrecht, Netherlands Univ Med Ctr Leiden, Dept Radiotherapy, RC Leiden, Netherlands Univ Med Ctr Leiden RC Leiden Netherlands erapy, RC Leiden, Netherlands Univ Utrecht, Ctr Biostat, Utrecht, Netherlands Univ Utrecht Utrecht Netherlands cht, Ctr Biostat, Utrecht, Netherlands St Antonius Hosp, Dept Pulm Dis, Nieuwegein, Netherlands St Antonius HospNieuwegein Netherlands lm Dis, Nieuwegein, Netherlands Univ Med Ctr, Dept Pulm Dis, Utrecht, Netherlands Univ Med Ctr Utrecht Netherlands r, Dept Pulm Dis, Utrecht, Netherlands
Titolo Testata:
RESPIRATORY MEDICINE
fascicolo: 3, volume: 95, anno: 2001,
pagine: 235 - 236
SICI:
0954-6111(200103)95:3<235:PCIILD>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
BRAIN METASTASES; RADIOTHERAPY; SURVIVORS; CARCINOMA;
Keywords:
small-cell lung cancer; prophylactic cranial irradiation; brain metastases;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Struikmans, H Univ Med Ctr, Dept Radiotherapy, Heidelberglaan 100, NL-3584CX Utrecht, Netherlands Univ Med Ctr Heidelberglaan 100 Utrecht Netherlands NL-3584 CX
Citazione:
Y.M. van der Linden et al., "Prophylactic cranial irradiation in limited disease small-cell lung cancerin complete remission: a retrospective analysis", RESP MED, 95(3), 2001, pp. 235-236

Abstract

Recently a meta-analysis showed an improved survival probability of prophylactic cranial irradiation (PCI) in limited disease small-cell lung cancer (LD SCLC) in complete remission after chemotherapy. We evaluated treatment results of PCI+ and PCI- in these patients. WhetherPCI (n = 65) or no PCI (n = 37) was administered did not depend either on patients or on tumour characteristics. After 2 years the incidence of brain metastases was 11% in PCI- patients and 51% in PCI- patients. Both disease-free survival and overall survival were significantly longer after PCI. PCI reduces the incidence of brain metastases, prolongs brain metastases-free period, and overall survival in LD SCLC patients in complete remission after chemotherapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 11:05:34