Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Effects of risperidone on event-related potentials in schizophrenic patients
Autore:
Iwanami, A; Okajima, Y; Isono, H; Shinoda, J; Kasai, K; Hata, A; Fukuda, M; Nakagome, K; Kamijima, K;
Indirizzi:
Univ Tokyo, Fac Med, Dept Neuropsychiat, Bunkyo Ku, Tokyo 1138655, Japan Univ Tokyo Tokyo Japan 1138655 psychiat, Bunkyo Ku, Tokyo 1138655, Japan Showa Univ, Sch Med, Dept Psychiat, Tokyo, Japan Showa Univ Tokyo JapanShowa Univ, Sch Med, Dept Psychiat, Tokyo, Japan Gunma Univ, Fac Med, Dept Neuropsychiat, Gunma, Japan Gunma Univ Gunma Japan Univ, Fac Med, Dept Neuropsychiat, Gunma, Japan
Titolo Testata:
PHARMACOPSYCHIATRY
fascicolo: 2, volume: 34, anno: 2001,
pagine: 73 - 79
SICI:
0176-3679(200103)34:2<73:EOROEP>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
TREATMENT-RESISTANT SCHIZOPHRENIA; NEGATIVE SYMPTOMS; P300 COMPONENT; WORKING-MEMORY; REACTION-TIME; HALOPERIDOL; LATENCY; ABNORMALITIES; ATTENUATION; MEDICATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Iwanami, A Univ Tokyo, Fac Med, Dept Neuropsychiat, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Japan Univ Tokyo 7-3-1 Hongo Tokyo Japan 1138655 okyo 1138655, Japan
Citazione:
A. Iwanami et al., "Effects of risperidone on event-related potentials in schizophrenic patients", PHARMACOPS, 34(2), 2001, pp. 73-79

Abstract

In order to examine the effects of risperidone on cognitive impairment in schizophrenia, event-related potentials (ERPs) were recorded before and after switching from conventional neuroleptics to risperidone in schizophrenicpatients. ERPs were recorded during two auditory discrimination tasks (an oddball taste and a distraction task) in 10 medicated schizophrenic patients during conventional neuroleptic and risperidone treatments. The amplitudes and latencies of N 100 and P 300 component were measured in ERPs for target stimuli in the oddball taste and in ERPs for target and novel stimuli inthe distraction task. Although N 100 amplitude and latency and P 300 amplitude did not change significantly after switching the drug compared to thatduring conventional neuroleptic treatment, P 300 latency for target stimuli shortened significantly during risperidone treatment in both tasks, accompanied by the shortening of the reaction time in the distraction task. The P 300 latency change did not correlate with the change of the severity of psychopathology. These findings suggest that risperidone may speed the information processing in schizophrenic patients, contributing to the improvement of cognitive functions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 06:56:38