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Titolo:
Day/night variations of dopamine ocular content during Xenopos laevis ontogeny
Autore:
Delgado, MJ; Cespedes, MV; De Pedro, N; Alonso-Bedate, M; Alonso-Gomez, AL;
Indirizzi:
Univ Complutense, Fac Biol, Dept Biol Anim Fioiol Anim 2, Madrid 28040, Spain Univ Complutense Madrid Spain 28040 m Fioiol Anim 2, Madrid 28040, Spain
Titolo Testata:
NEUROSCIENCE LETTERS
fascicolo: 3, volume: 300, anno: 2001,
pagine: 129 - 132
SICI:
0304-3940(20010316)300:3<129:DVODOC>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
TYROSINE-HYDROXYLASE; ENDOGENOUS DOPAMINE; AMACRINE CELLS; FROG RETINA; LIGHT; SEROTONIN; STIMULATION; ADAPTATION; MELATONIN; RELEASE;
Keywords:
dopamine; retina; Xenopus; ontogeny; eyecup culture; light/dark cycle; high pressure liquid chromatography/electrochemical detection;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Delgado, MJ Univ Complutense, Fac Biol, Dept Biol Anim Fioiol Anim 2, Madrid 28040, Spain Univ Complutense Madrid Spain 28040 m 2, Madrid 28040, Spain
Citazione:
M.J. Delgado et al., "Day/night variations of dopamine ocular content during Xenopos laevis ontogeny", NEUROSCI L, 300(3), 2001, pp. 129-132

Abstract

Concentration of dopamine (DA) and its metabolite, 3,4-dihydroxyphenylacetic acid is quantified by high-pressure liquid chromatography with a coulometric detection system in the eye of Xenopus laevis through ontogeny and in adults at two times during photocycle (midday and midnight). Ocular dopaminergic activity remains low during pre- and prometamorphosis and significantly rises in postmetamorphic froglets. This increase is more pronounced at midnight than at midday. The dualism of DA content versus DA release in Xenopus ocular tissue is studied in an eyecup culture system. On a 24-h cycle of DA release from adult Xenopus eyecups the highest DA release by eyecups is produced during daytime, and significantly decreases in darkness. From these results it can be concluded that in spite of the early development of the retinal dopaminergic system in the ontogeny of Xenopus, the final maturation must occur during the metamorphic climax. Endogenous DA release is significantly inhibited by light offset, which explains the higher ocular DA content found at midnight as compared to midday in postmetamorphic froglets and adults. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 05:40:59