Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Antigen processing by the proteasome
Autore:
Kloetzel, PM;
Indirizzi:
Humboldt Univ, Charite, Fac Med, Inst Biochem, D-10117 Berlin, Germany Humboldt Univ Berlin Germany D-10117 st Biochem, D-10117 Berlin, Germany
Titolo Testata:
NATURE REVIEWS MOLECULAR CELL BIOLOGY
fascicolo: 3, volume: 2, anno: 2001,
pagine: 179 - 187
SICI:
1471-0072(200103)2:3<179:APBTP>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
MHC CLASS-I; NEWLY SYNTHESIZED PROTEINS; T-CELL EPITOPE; 20S PROTEASOME; REGULATORY PARTICLE; INTERFERON-GAMMA; 20-S PROTEASOME; CTL EPITOPE; MULTICATALYTIC PROTEINASE; RAPID DEGRADATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
88
Recensione:
Indirizzi per estratti:
Indirizzo: Kloetzel, PM Humboldt Univ, Charite, Fac Med, Inst Biochem, Monbijoustr 2,D-10117 Berlin, Germany Humboldt Univ Monbijoustr 2 Berlin Germany D-10117 , Germany
Citazione:
P.M. Kloetzel, "Antigen processing by the proteasome", NAT REV MOL, 2(3), 2001, pp. 179-187

Abstract

The proteasome is an essential part of our immune surveillance mechanisms:by generating peptides from intracellular antigens it provides peptides that are then 'presented' to T cells. But proteasomes - the waste-disposal units of the cell - typically do not generate peptides for antigen presentation with high efficiency. How, then, does the proteasome adapt to serve the immune system well?.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/10/20 alle ore 22:49:38