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Titolo:
Extracting parametric images from dynamic contrast-enhanced MRI studies ofthe brain using factor analysis
Autore:
Martel, AL; Moody, AR; Allder, SJ; Delay, GS; Morgan, PS;
Indirizzi:
Univ Nottingham Hosp, Queens Med Ctr, Dept Phys Med, Nottingham NG7 2UH, England Univ Nottingham Hosp Nottingham England NG7 2UH tingham NG7 2UH, England Univ Nottingham Hosp, Queens Med Ctr, Dept Acad Radiol, Nottingham NG7 2UH, England Univ Nottingham Hosp Nottingham England NG7 2UH tingham NG7 2UH, England Univ Nottingham Hosp, Queens Med Ctr, Dept Clin Neurol, Nottingham NG7 2UH, England Univ Nottingham Hosp Nottingham England NG7 2UH tingham NG7 2UH, England
Titolo Testata:
MEDICAL IMAGE ANALYSIS
fascicolo: 1, volume: 5, anno: 2001,
pagine: 29 - 39
SICI:
1361-8415(200103)5:1<29:EPIFDC>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-VOLUME; PRINCIPAL-COMPONENTS; MAGNETIC-RESONANCE; HYPERACUTE STROKE; NORMAL VALUES; FLOW; HEMODYNAMICS; RADIONUCLIDE; SEQUENCES; ISCHEMIA;
Keywords:
magnetic resonance imaging; contrast enhancement; brain blood flow; factor analysis; stroke;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Engineering, Computing & Technology
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Martel, AL Univ Nottingham Hosp, Queens Med Ctr, Dept Phys Med, Derby Rd, Nottingham NG7 2UH, England Univ Nottingham Hosp Derby Rd Nottingham England NG7 2UH gland
Citazione:
A.L. Martel et al., "Extracting parametric images from dynamic contrast-enhanced MRI studies ofthe brain using factor analysis", MED IMAGE A, 5(1), 2001, pp. 29-39

Abstract

Factor analysis of dynamic studies (FADS) is a technique that allows structures with different temporal characteristics to be extracted from dynamic contrast enhanced studies without making any a priori assumptions about physiology. These dynamic structures may correspond to different tissue types or different organs or they may simply be a useful way of characterising the data. This paper describes a method of automatically extracting factor images and curves from contrast enhanced MRI studies of the brain. This method has been applied to 107 studies carried out on patients with acute stroke. The results show that FADS is able to extract factor curves correlated toarterial and venous signal intensity curves and that the corresponding factor images allow a distinction to be made between areas of the brain with normal and abnormal perfusion. The method is robust and can be applied routinely to dynamic studies of the brain. The constraints described are sufficiently general to be applicable to other dynamic MRI contrast enhanced studies where an increase in contrast concentration produces an increase in signal intensity. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 03:03:46