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Titolo:
Employment and alcohol use after liver transplantation for alcoholic and nonalcoholic liver disease: A systematic review
Autore:
Bravata, DM; Olkin, I; Barnato, AE; Keeffe, EB; Owens, DK;
Indirizzi:
Dept Vet Affairs Hlth Care Syst, Palo Alto, CA USA Dept Vet Affairs Hlth Care Syst Palo Alto CA USA Syst, Palo Alto, CA USA Stanford Univ, Sch Med, Ctr Primary Care & Outcomes Res, Dept Med, Stanford, CA USA Stanford Univ Stanford CA USA & Outcomes Res, Dept Med, Stanford, CA USA Stanford Univ, Sch Med, Dept Med, Div Gastroenterol, Stanford, CA USA Stanford Univ Stanford CA USA t Med, Div Gastroenterol, Stanford, CA USA Stanford Univ, Sch Med, Stanford Med Informat, Stanford, CA USA Stanford Univ Stanford CA USA d, Stanford Med Informat, Stanford, CA USA Stanford Univ, Sch Med, Dept Hlth Res & Policy, Stanford, CA USA Stanford Univ Stanford CA USA , Dept Hlth Res & Policy, Stanford, CA USA Stanford Univ, Sch Educ, Stanford, CA USA Stanford Univ Stanford CA USAStanford Univ, Sch Educ, Stanford, CA USA Stanford Univ, Dept Stat, Stanford, CA USA Stanford Univ Stanford CA USAStanford Univ, Dept Stat, Stanford, CA USA
Titolo Testata:
LIVER TRANSPLANTATION
fascicolo: 3, volume: 7, anno: 2001,
pagine: 191 - 203
SICI:
1527-6465(200103)7:3<191:EAAUAL>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
QUALITY-OF-LIFE; HEPATIC TRANSPLANTATION; FOLLOW-UP; PSYCHOLOGICAL HEALTH; CIRRHOSIS; SURVIVAL; RECIPIENTS; RECIDIVISM; SELECTION; EFFICACY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
98
Recensione:
Indirizzi per estratti:
Indirizzo: Bravata, DM 179 Encina Commons, Stanford, CA 94305 USA 179 Encina CommonsStanford CA USA 94305 anford, CA 94305 USA
Citazione:
D.M. Bravata et al., "Employment and alcohol use after liver transplantation for alcoholic and nonalcoholic liver disease: A systematic review", LIVER TRANS, 7(3), 2001, pp. 191-203

Abstract

The purpose of the study is to evaluate patterns of employment and alcoholuse among liver transplant recipients with alcoholic (ALD) and nonalcoholic liver disease (non-ALD), MEDLINE, EMBASE, and bibliographic searches identified 5,505 potentially relevant articles published between January 1966 and October 1998. Eighty-two studies reporting data on 5,020 transplant recipients met our inclusion criteria. Pre-orthotopic liver transplantation (OLT), 29% of transplant recipients with ALD and 59% of those with non-ALD worked versus 33% and 80% at 3 years for transplant recipients with ALD and non-ALD, respectively (P <.00001 for each interval). We found no difference in the proportion of transplant recipients with ALD and non-ALD reporting early alcohol use post-OLT: 4% versus 5% at 6 months and 17% versus 16% at 12months. However, among post-OLT drinkers, transplant recipients with non-ALD were more likely to drink moderately and those with ALD to drink excessively. At 7 years post-OLT, 32% of the patients with ALD reported using alcohol. The odds ratio for alcohol use among patients who maintained abstinence for fewer than 6 months pre-OLT versus those who maintained abstinence for greater than 6 months was 7.8 (95% confidence interval, 4.0 to 15.3). Before OLT and at long-term follow-up, substantially more transplant recipients with non-ALD than ALD were employed. The proportions of transplant recipients with ALD and non-ALD reporting alcohol use did not differ, although those with ALD tended to consume greater quantities.

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Documento generato il 18/01/20 alle ore 11:16:51