Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Molecular cloning of feline hepatocyte growth factor (HGF) cDNA
Autore:
Kobayashi, Y; Nakamura, N; Ishizaka, T; Masuda, K; Ohno, K; Tsujimoto, H;
Indirizzi:
Univ Tokyo, Fac Agr, Dept Vet Internal Med, Bunkyo Ku, Tokyo 113, Japan Univ Tokyo Tokyo Japan 113 Vet Internal Med, Bunkyo Ku, Tokyo 113, Japan
Titolo Testata:
JOURNAL OF VETERINARY MEDICAL SCIENCE
fascicolo: 2, volume: 63, anno: 2001,
pagine: 211 - 214
SICI:
0916-7250(200102)63:2<211:MCOFHG>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEPATIC-FAILURE; RENAL-FAILURE; RATS; REGENERATION; LIVER; MICE; IDENTITY; INJURY; MET;
Keywords:
cloning; feline; hepatocyte growth factor (HGF);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Kobayashi, Y Univ Tokyo, Fac Agr, Dept Vet Internal Med, Bunkyo Ku, 1-1-1 Yayoi, Tokyo 113, Japan Univ Tokyo 1-1-1 Yayoi Tokyo Japan 113 yoi, Tokyo 113, Japan
Citazione:
Y. Kobayashi et al., "Molecular cloning of feline hepatocyte growth factor (HGF) cDNA", J VET MED S, 63(2), 2001, pp. 211-214

Abstract

Hepatocyte growth factor (HGF) is a pleiotropic cytokine responsible for regeneration, development and maintenance of various organs, and growth, invasion and metastasis of tumor cells. A full-length feline HGF cDNA was cloned and sequenced by RT-PCR from cat liver. Feline HGF consists of 728 aminoacid and contains alpha- and beta -chains encoded in a single open readingframe. The predicted amino acid sequence of feline HGF showed 93.2, 93.3 and 93.3% homology with those of human, mouse and rat HGF, respectively. Theputative proteolytic processing site, all cysteine residues, and four potential glycosylation sites are conserved in all species. Therefore, feline HGF is expected to have a similar three-dimensional structure to human, mouse and rat HGF.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 00:50:26