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Titolo:
Persistent presence of Bacteroides forsythus as a risk factor for attachment loss in a population with low prevalence and severity of adult periodontitis
Autore:
Tran, SD; Rudney, JD; Sparks, BS; Hodges, JS;
Indirizzi:
Univ Minnesota, Sch Dent, Dept Oral Sci, Minneapolis, MN 55455 USA Univ Minnesota Minneapolis MN USA 55455 al Sci, Minneapolis, MN 55455 USA Univ Minnesota, Sch Dent, Minnesota Oral Hlth Clin Res Ctr, Biostat Core, Minneapolis, MN 55455 USA Univ Minnesota Minneapolis MN USA 55455 t Core, Minneapolis, MN 55455 USA
Titolo Testata:
JOURNAL OF PERIODONTOLOGY
fascicolo: 1, volume: 72, anno: 2001,
pagine: 1 - 10
SICI:
0022-3492(200101)72:1<1:PPOBFA>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
POLYMERASE CHAIN-REACTION; RNA GENE PRIMERS; ACTINOBACILLUS-ACTINOMYCETEMCOMITANS; PORPHYROMONAS-GINGIVALIS; SUBGINGIVAL PLAQUE; LONGITUDINAL DATA; DISEASE; MICROBIOTA; GINGIVITIS; PARAMETERS;
Keywords:
Actinobacillus actinomycetemcomitans; Bacteroides forsythus; Porphyromonas gingivalis; follow-up studies; periodontal diseases, microbiology; periodontal attachment loss, microbiology; risk factors;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Tran, SD NIDCR, Gene Therapy & Therapeut Branch, NIH, MSC 1190, Bldg 10,Room 1N113,10 Ctr Dr, Bethesda, MD 20892 USA NIDCR Bldg 10,Room 1N113,10 Ctr Dr Bethesda MD USA 20892 0892 USA
Citazione:
S.D. Tran et al., "Persistent presence of Bacteroides forsythus as a risk factor for attachment loss in a population with low prevalence and severity of adult periodontitis", J PERIODONT, 72(1), 2001, pp. 1-10

Abstract

Background: Previous longitudinal studies investigating the role of microorganisms in periodontitis have focused on subjects with a high prevalence and severity of disease. The complex profile of microbial species in severe cases of periodontitis might not allow us to differentiate which bacterial species initiate disease or which species simply proliferate after disease progression. This prospective longitudinal study followed a group of 205 subjects who showed a low prevalence and severity of adult periodontitis, andthus allowed us to monitor early microbiological changes in the development of periodontitis. Methods: Subgingival plaque was collected from proximal surfaces of a posterior sextant at 6-month intervals for 2 years. During the monitoring period, 44 subjects had either attachment loss or attachment gain. Using multiplex polymerase chain reaction (PCR), all plaque samples from those 44 subjects were analyzed for the presence of Actinobacillus actinomycetemcomitans, Bacteroides forsythus, and Porphyromonas gingivalis. Results: Both subjects with attachment loss and those with attachment gainbad a high prevalence of these 3 periodontal pathogens. The mere presence of any of the 3 species at a site could not predict future attachment loss at that specific site. However, subjects with a persistent presence of B. forsythus at any site across all visits had 5.3 times higher odds of having at least one site in their mouth losing attachment compared to subjects with occasional or no presence of B, forsythus. Conclusions: The persistence of B. forsythus identified subjects at higherrisk, but not which specific sites in those subjects would lose attachment.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/10/20 alle ore 00:10:52