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Titolo:
Special nutritional needs of infants for prevention of and recovery from bronchopulmonary dysplasia
Autore:
Atkinson, SA;
Indirizzi:
McMaster Univ, Fac Hlth Sci, Dept Pediat, Hamilton, ON L8N 3Z5, Canada McMaster Univ Hamilton ON Canada L8N 3Z5 at, Hamilton, ON L8N 3Z5, Canada
Titolo Testata:
JOURNAL OF NUTRITION
fascicolo: 3, volume: 131, anno: 2001,
pagine: 942S - 946S
SICI:
0022-3166(200103)131:3<942S:SNNOIF>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
VITAMIN-A SUPPLEMENTATION; BIRTH-WEIGHT INFANTS; PREMATURE-INFANTS; PRETERM INFANTS; DEXAMETHASONE TREATMENT; RANDOMIZED TRIAL; BONE METABOLISM; GROWTH; DISCHARGE; PIGLETS;
Keywords:
bronchopulmonary dysplasia; premature infants; dexamethasone; enriched formula; bone mineral content;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Atkinson, SA McMaster Univ, Fac Hlth Sci, Dept Pediat, HSC 3V42,1200 Main St W, Hamilton, ON L8N 3Z5, Canada McMaster Univ HSC 3V42,1200 Main St W Hamilton ON Canada L8N 3Z5
Citazione:
S.A. Atkinson, "Special nutritional needs of infants for prevention of and recovery from bronchopulmonary dysplasia", J NUTR, 131(3), 2001, pp. 942S-946S

Abstract

Extremely low birth weight infants who develop severe respiratory disease may have special nutrient requirements imposed by a combination of enhancedutilization of nutrients or the need for epithelial cell repair resulting from the disease process, as well as to support catch-up growth, Inositol, free fatty acids, vitamin E and vitamin A are proposed as nutrients for which infants at risk of chronic pulmonary insufficiency may have special requirements. Of these nutrients, only for vitamin A does suggestive evidence exist that high doses when given intramuscularly may reduce the incidence ofdeath or chronic lung disease, Exogenous steroid therapy (dexamethasone), which is often used to improve pulmonary compliance in ventilated prematureinfants, may compromise vitamin A status and induce restricted somatic andbone mineral growth. Supplemental nutrition by means of enriched infant formulas has provided benefits in growth and bone mass accretion to infants recovering from bronchopulmonary dysplasia up to 3-mo corrected age. This growth advantage was not sustained over the subsequent 9 mo, suggesting that prolonged nutritional support is required until catch-up growth is complete. Further studies are required to delineate the needs for specific nutrients such as antioxidant vitamins and minerals or vitamin A that may play a role in preventing severe chronic lung disease in premature infants, As well,the role of supplemental nutrition (beyond the requirements of term infants) to support catch-up growth and maintenance during the critical stages ofearly development requires further investigation before evidence-based nutrient recommendations can be developed for this special population of infants.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 10:27:31