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Titolo:
Detection of Treponema denticola in atherosclerotic lesions
Autore:
Okuda, K; Ishihara, K; Nakagawa, T; Hirayama, A; Inayama, Y; Okuda, K;
Indirizzi:
Tokyo Dent Coll, Dept Microbiol, Mihama Ku, Chiba, Japan Tokyo Dent Coll Chiba Japan ll, Dept Microbiol, Mihama Ku, Chiba, Japan Tokyo Dent Coll, Dept Periodont, Chiba, Japan Tokyo Dent Coll Chiba Japan kyo Dent Coll, Dept Periodont, Chiba, Japan Tokyo Dent Coll, Oral Hlth Sci Ctr, Chiba, Japan Tokyo Dent Coll Chiba Japan Dent Coll, Oral Hlth Sci Ctr, Chiba, Japan Yokohama City Univ, Sch Med, Dept Bacteriol, Yokohama, Kanagawa 232, JapanYokohama City Univ Yokohama Kanagawa Japan 232 ohama, Kanagawa 232, Japan Yokohama City Univ, Sch Med, Dept Anat & Surg Pathol, Yokohama, Kanagawa 232, Japan Yokohama City Univ Yokohama Kanagawa Japan 232 ohama, Kanagawa 232, Japan
Titolo Testata:
JOURNAL OF CLINICAL MICROBIOLOGY
fascicolo: 3, volume: 39, anno: 2001,
pagine: 1114 - 1117
SICI:
0095-1137(200103)39:3<1114:DOTDIA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY HEART-DISEASE; POLYMERASE CHAIN-REACTION; CHLAMYDIA-PNEUMONIAE; CARDIOVASCULAR-DISEASE; PERIODONTAL PATHOGENS; MYOCARDIAL-INFARCTION; DENTAL INFECTIONS; ASSOCIATION; DENTILISIN; PLAQUES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Okuda, K Tokyo Dent Coll, Dept Microbiol, Mihama Ku, 1-2-2 Masago, Chiba, Japan Tokyo Dent Coll 1-2-2 Masago Chiba Japan 2 Masago, Chiba, Japan
Citazione:
K. Okuda et al., "Detection of Treponema denticola in atherosclerotic lesions", J CLIN MICR, 39(3), 2001, pp. 1114-1117

Abstract

We examined 26 atherosclerotic lesions and 14 nondiseased aorta specimens to detect the periodontopathogenic part of the bacterial 16S rRNA locus by PCR. Treponema denticola sequence of the 16S rRNA locus was found in 6 out of 26 DNA samples (23.1%) from the formalin-fixed, paraffin-embeded atherosclerotic lesions obtained during surgery but not in any of the 14 nondiseased aorta samples from deceased persons. Utilizing immunofluorescence microscopy, we observed aggregated antigenic particles reacting with rabbit antiserum against T. denticola in thin sections of the PCR-positive samples, butwe could not detect any reacting particles in the PCR-negative thin sections.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 21:08:56