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Titolo:
Histochemical localisation of versican, aggrecan and hyaluronan in the developing condylar cartilage of the fetal rat mandible
Autore:
Shibata, S; Fukada, K; Suzuki, S; Ogawa, T; Yamashita, Y;
Indirizzi:
Tokyo Med & Dent Univ, Grad Sch, Dept Maxillofacial Biol, Bunkyo Ku, Tokyo1138510, Japan Tokyo Med & Dent Univ Tokyo Japan 1138510 Bunkyo Ku, Tokyo1138510, Japan Tokyo Med & Dent Univ, Grad Sch, Dept Maxillofacial Reconstruct & Funct, Tokyo 1138510, Japan Tokyo Med & Dent Univ Tokyo Japan 1138510 & Funct, Tokyo 1138510, Japan
Titolo Testata:
JOURNAL OF ANATOMY
, volume: 198, anno: 2001,
parte:, 2
pagine: 129 - 135
SICI:
0021-8782(200102)198:<129:HLOVAA>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROTEOGLYCAN PG-M; CHONDROITIN SULFATE; DENTAL-PULP; EXTRACELLULAR-MATRIX; ALKALINE-PHOSPHATASE; II COLLAGEN; PROTEIN; LOCALIZATION; OUTGROWTH; TISSUES;
Keywords:
mandibular condyle; proteoglycans; cartilage;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Shibata, S Tokyo Med & Dent Univ, Grad Sch, Dept Maxillofacial Biol, Bunkyo Ku, 1-5-45 Yushima, Tokyo 1138510, Japan Tokyo Med & Dent Univ 1-5-45 Yushima Tokyo Japan 1138510 Japan
Citazione:
S. Shibata et al., "Histochemical localisation of versican, aggrecan and hyaluronan in the developing condylar cartilage of the fetal rat mandible", J ANAT, 198, 2001, pp. 129-135

Abstract

We investigated the histochemical localisation of versican, aggrecan and hyaluronan in the developing condylar cartilage of the fetal rat mandible atd 15-17 of gestation, At d 15 of gestation, immunostaining for versican was detected in the anlage of the future condylar process (condylar anlage), although the staining intensity showed a considerable regional variation. At d 16 of gestation, a metachromatically stained matrix firstly appeared inthe condylar anlage. Aggrecan, hyaluronan and versican were simultaneouslydetected in this newly formed condylar cartilage. At d 17 of gestation, immunostaining for versican became restricted to the perichondrium and was barely detected in the cartilage. Colocalisation of versican and aggrecan wasalso seen in the cranial base cartilage at d 14 of gestation. These results indicate that although versican is replaced by aggrecan during the transition from prechondrogenic tissue to cartilage, both molecules were temporally colocalised in the newly formed cartilage. A hyaluronan-rich, low-versican area was identified in the posterior end of the condylar anlage during d15-17 of gestation. The existence of this area is a unique structural feature of the developing condylar cartilage.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 13:14:12