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Titolo:
Exploration of mosquito immunity using cells in culture
Autore:
Fallon, AM; Sun, DX;
Indirizzi:
Univ Minnesota, Dept Entomol, St Paul, MN 55108 USA Univ Minnesota St Paul MN USA 55108 , Dept Entomol, St Paul, MN 55108 USA
Titolo Testata:
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
fascicolo: 3, volume: 31, anno: 2001,
pagine: 263 - 278
SICI:
0965-1748(20010301)31:3<263:EOMIUC>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
VECTOR ANOPHELES-GAMBIAE; SARCOPHAGA LECTIN GENE; YELLOW-FEVER MOSQUITO; PEREGRINA FLESH FLY; AEDES-AEGYPTI; INSECT IMMUNITY; KAPPA-B; MOLECULAR CHARACTERIZATION; ANTIBACTERIAL PEPTIDE; HEMOCYTE POPULATIONS;
Keywords:
established cell line; hemocyte; immune response; innate immunity; cecropin; defensin; transferrin; lysozyme;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
135
Recensione:
Indirizzi per estratti:
Indirizzo: Fallon, AM Univ Minnesota, Dept Entomol, 1980 Folwell Ave, St Paul, MN 55108 USA Univ Minnesota 1980 Folwell Ave St Paul MN USA 55108 55108 USA
Citazione:
A.M. Fallon e D.X. Sun, "Exploration of mosquito immunity using cells in culture", INSEC BIO M, 31(3), 2001, pp. 263-278

Abstract

The propagation of immune-responsive cells in vitro has provided the basisfor substantial contributions to our understanding of many aspects of the mammalian immune response. In contrast, the potential for exploring the innate immune response of insects using cultured cells is only beginning to bedeveloped, particularly with various mosquito cell lines from the genera Aedes and Anopheles. Immune-reactive mosquito cell lines express various defensive factors, including transferrin, lysozyme, cecropin, defensin, and prophenoloxidase activities. In this review, we discuss insect immunity in the context of key concepts that have emerged in the study of the mammalian immune system, with emphasis on the properties of the cells that participatein the immune response. The nature of established cell lines and their contributions to our understanding of immune functions in humans and insects is described, with emphasis on our own work with the C7-10 and Aag-2 mosquito cell lines from Aedes albopictus and Aedes aegypti, respectively. Finally, we offer some speculation on further advances in insect immunology that may be facilitated by work with cells in culture. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 13:07:40