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Titolo:
Clear cell variant of malignant melanoma of the uterine cervix: A case report and review of the literature
Autore:
Furuya, M; Shimizu, M; Nishihara, H; Ito, T; Sakuragi, N; Ishikura, H; Yoshiki, T;
Indirizzi:
Hokkaido Univ Hosp, Dept Surg Pathol, Sapporo, Hokkaido 0608638, Japan Hokkaido Univ Hosp Sapporo Hokkaido Japan 0608638 Hokkaido 0608638, Japan Hokkaido Univ, Sch Med, Dept Gynecol, Sapporo, Hokkaido 060, Japan Hokkaido Univ Sapporo Hokkaido Japan 060 ol, Sapporo, Hokkaido 060, Japan Chiba Univ, Sch Med, Dept Pathol, Chiba 280, Japan Chiba Univ Chiba Japan 280 Univ, Sch Med, Dept Pathol, Chiba 280, Japan
Titolo Testata:
GYNECOLOGIC ONCOLOGY
fascicolo: 3, volume: 80, anno: 2001,
pagine: 409 - 412
SICI:
0090-8258(200103)80:3<409:CCVOMM>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
SOFT PARTS; SARCOMA;
Keywords:
malignant melanoma; uterine cervix; clear cell;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Yoshiki, T Hokkaido Univ, Grad Sch Med, Dept Pathol, Kita Ku, North 15,West 7, Sapporo, Hokkaido 0608638, Japan Hokkaido Univ North 15,West 7 SapporoHokkaido Japan 0608638 an
Citazione:
M. Furuya et al., "Clear cell variant of malignant melanoma of the uterine cervix: A case report and review of the literature", GYNECOL ONC, 80(3), 2001, pp. 409-412

Abstract

Background. A rare variant of malignant melanoma of the uterine cervix mimicking clear cell carcinoma or clear cell sarcoma is described. Case. A 33-year-old Japanese woman was admitted to the hospital complaining of genital discharge and lower back pain. The stage was FIGO IIB and radical hysterectomy and pelvic lymphadenectomy were done. Pathological examination, immunohistochemical studies of melanin granules, and molecular analysis of the EWS/ATF-1 fusion gene were also done. A diffuse proliferation of amelanotic clear cells was detected in the uterine cervix. Tumor cells werepositive for HMB 45, Melan-A (MART-1), and S-100 protein and negative for epithelial markers. The EWS/ATF-1 fusion gene was not detected. Conclusion. This is apparently the first report of a case of clear cell melanoma of the uterine cervix. Despite its rarity, this variant of malignantmelanoma should be considered when diagnosing clear cell neoplasms of the uterine cervix. (C) 2001 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 18:21:07