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Titolo:
Members of the low density lipoprotein receptor family control diverse physiological processes
Autore:
Argraves, WS;
Indirizzi:
Med Univ S Carolina, Dept Cell Biol & Anat, Charleston, SC 29425 USA Med Univ S Carolina Charleston SC USA 29425 nat, Charleston, SC 29425 USA
Titolo Testata:
FRONTIERS IN BIOSCIENCE
, volume: 6, anno: 2001,
pagine: D406 - D416
SICI:
1093-9946(200103)6:<D406:MOTLDL>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROTEIN ALPHA-2-MACROGLOBULIN RECEPTOR; PLASMINOGEN-ACTIVATOR INHIBITOR-1; CELL-SURFACE PROTEOGLYCANS; AMYLOID PRECURSOR PROTEIN; FACTOR PATHWAY INHIBITOR; OOCYTE-SPECIFIC MEMBERS; ENDOCYTIC RECEPTOR; MEDIATES ENDOCYTOSIS; ALPHA(2)-MACROGLOBULIN RECEPTOR; BINDING-PROTEIN;
Keywords:
LDL receptor; LRP; megalin; LRP-2; VLDLR; ApoER2; review;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
110
Recensione:
Indirizzi per estratti:
Indirizzo: Argraves, WS Med Univ S Carolina, Dept Cell Biol & Anat, 171 Ashley Ave, Charleston, SC29425 USA Med Univ S Carolina 171 Ashley Ave Charleston SC USA29425 SA
Citazione:
W.S. Argraves, "Members of the low density lipoprotein receptor family control diverse physiological processes", FRONT BIOSC, 6, 2001, pp. D406-D416

Abstract

The low density lipoprotein receptor (LDLR) family is a group of receptorsthat mediate endocytosis leading to lysosomal degradation of an enormous repertoire of ligands. To date, over 50 distinct macromolecules have been shown to bind members of the family. This wide spectrum of ligand recognitionis the basis for an immense diversity in physiological processes in which these receptors participate. In this article, the physiological roles of the LDLR family members are briefly reviewed and a comprehensive list of the ligands with which the receptors interact is presented.The low density lipoprotein receptor (LDLR) family is a group of receptors that mediate endocytosis leading to lysosomal degradation of an enormous repertoire of ligands. To date, over 50 distinct macromolecules have been shown to bind members of the family. This wide spectrum of ligand recognition is the basis for an immense diversity in physiological processes in which these receptors participate. In this article, the physiological roles of the LDLR family membersare briefly reviewed and a comprehensive list of the ligands with which the receptors interact is presented.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 01:17:15