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Titolo:
Development of a profitable procedure for the extraction of 2-H-1-benzopyran-2-one (coumarin) from Mikania glomerata
Autore:
Cabral, LM; dos Santos, TC; Alhaique, F;
Indirizzi:
Univ Rome La Sapienza, Dip Studi Chim & Tecnol Sostanze Biologicamente A, I-00185 Rome, Italy Univ Rome La Sapienza Rome Italy I-00185 icamente A, I-00185 Rome, Italy Univ Fed Rio de Janeiro, Fac Farm, CCS, Dept Medicamentos, BR-21941 Rio DeJaneiro, Brazil Univ Fed Rio de Janeiro Rio De Janeiro Brazil BR-21941 DeJaneiro, Brazil
Titolo Testata:
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
fascicolo: 1, volume: 27, anno: 2001,
pagine: 103 - 106
SICI:
0363-9045(2001)27:1<103:DOAPPF>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERFORMANCE LIQUID-CHROMATOGRAPHY; ANGELICA-ARCHANGELICA;
Keywords:
Mikania glomerata; extraction procedure; coumarin; phytopharmaceutical technology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Alhaique, F Univ Rome La Sapienza, Dip Studi Chim & Tecnol Sostanze Biologicamente A, Piazzale A Moro 5, I-00185 Rome, Italy Univ Rome La Sapienza Piazzale A Moro 5 Rome Italy I-00185 ly
Citazione:
L.M. Cabral et al., "Development of a profitable procedure for the extraction of 2-H-1-benzopyran-2-one (coumarin) from Mikania glomerata", DRUG DEV IN, 27(1), 2001, pp. 103-106

Abstract

This report deals with a new procedure suitable for the extraction of coumarin 1 from Mikania glomerata. The aim of this investigation is to obtain this compound in an economically profitable way, taking into account the yield of its extraction, the cost, and the time of the overall process. Fresh and dried plants collected in several areas of the State of Rio de Janeiro were used, and seasonal effects on coumarin content were studied. Obtained results indicated that extraction with a 1% (w/v) NaOH solution, under appropriate conditions, allows a simple and complete recovery of the desired product and that the best yields were obtained with the fresh aerial parts ofthe plant. Season and area of harvesting effects have also been studied.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 02:42:30