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Titolo:
Study on tablet binding and disintegrating properties of alternative starches prepared from taro and sweet potato tubers
Autore:
Subhadhirasakul, S; Yuenyoungsawad, S; Ketjinda, W; Phadoongsombut, N; Faroongsarng, D;
Indirizzi:
Prince of Songkla Univ, Fac Pharmaceut Sci, Hat Yai 90112, Thailand Princeof Songkla Univ Hat Yai Thailand 90112 i, Hat Yai 90112, Thailand
Titolo Testata:
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
fascicolo: 1, volume: 27, anno: 2001,
pagine: 81 - 87
SICI:
0363-9045(2001)27:1<81:SOTBAD>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIRECT COMPRESSION; RICE STARCH;
Keywords:
alternative starch; taro; sweet potato; binder; disintegrant;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Faroongsarng, D Prince of Songkla Univ, Fac Pharmaceut Sci, Hat Yai 90112,Thailand Prince of Songkla Univ Hat Yai Thailand 90112 , Thailand
Citazione:
S. Subhadhirasakul et al., "Study on tablet binding and disintegrating properties of alternative starches prepared from taro and sweet potato tubers", DRUG DEV IN, 27(1), 2001, pp. 81-87

Abstract

To demonstrate the potential alternative sources of starch used in tablet formulations, starches from tare (TS) and sweet potato (SPS) tubers were prepared with obtained yields of 11.0 and 9.6%, respectively. Both TS and SPSmet USP22-NF17 identification and specifications. Their equilibrium moisture contents and gelatinization temperatures were comparable with those of commercial starch, whereas amylose contents of TS and SPS were 21.38% w/w and 41.76% w/w, respectively. Both were found to possess similar flow characteristics. To evaluate TS and SPS as granulating agents and disintegrants, tablets with controlled compression lends were prepared by incorporating a starch candidate with dibasic calcium phosphate in paste and powders forms, respectively. Tablets were then evaluated based on compressibility, friability, and disintegration. It was found that the binding and disintegrating performance of both TS and SPS was similar to that of commercial cornstarch.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 19:56:57