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Titolo:
Regulation of neural determination by evolutionarily conserved signals: anti-BMP factors and what next?
Autore:
Sasai, Y;
Indirizzi:
Kyoto Univ, Inst Frontier Med Sci, Dept Med Embryol & Neurobiol, Kyoto 6068507, Japan Kyoto Univ Kyoto Japan 6068507 Embryol & Neurobiol, Kyoto 6068507, Japan RIKEN, Ctr Dev Biol, Organogenesis & Neurogenesis Grp, Kobe, Hyogo 6500047, Japan RIKEN Kobe Hyogo Japan 6500047 urogenesis Grp, Kobe, Hyogo 6500047, Japan
Titolo Testata:
CURRENT OPINION IN NEUROBIOLOGY
fascicolo: 1, volume: 11, anno: 2001,
pagine: 22 - 26
SICI:
0959-4388(200102)11:1<22:RONDBE>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
DORSAL-VENTRAL PATTERN; DROSOPHILA EMBRYO; TWISTED GASTRULATION; SPEMANN ORGANIZER; XENOPUS EMBRYOS; VERTEBRATE EMBRYOS; ACTIVITY GRADIENT; GROWTH-FACTOR; INDUCTION; PROTEIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
58
Recensione:
Indirizzi per estratti:
Indirizzo: Sasai, Y Kyoto Univ, Inst Frontier Med Sci, Dept Med Embryol & Neurobiol, Kyoto 6068507, Japan Kyoto Univ Kyoto Japan 6068507 Neurobiol, Kyoto 6068507, Japan
Citazione:
Y. Sasai, "Regulation of neural determination by evolutionarily conserved signals: anti-BMP factors and what next?", CUR OP NEUR, 11(1), 2001, pp. 22-26

Abstract

The evolutionary conservation of Chordin/bone morphogenetic protein (BMP) signaling supports the hypothesis of dorsal-ventral axis inversion of vertebrates and invertebrates, and implies that the invention of a central nervous system occurred only once during animal evolution. This hypothesis is further strengthened by recent findings of the conservation of downstream genes and modifier genes of neural induction. On the other hand, in contrast with such gross conservation, recent data suggest that the requirement for some signals in neural determination may differ even within the vertebrate subphylum.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 07:15:25