Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Role of IL-12 in Staphylococcus aureus-triggered arthritis and sepsis
Autore:
Hultgren, OH; Stenson, M; Tarkowski, A;
Indirizzi:
Gothenburg Univ, Dept Rheumatol, S-41346 Gothenburg, Sweden Gothenburg Univ Gothenburg Sweden S-41346 ol, S-41346 Gothenburg, Sweden
Titolo Testata:
ARTHRITIS RESEARCH
fascicolo: 1, volume: 3, anno: 2001,
pagine: 41 - 47
SICI:
1465-9913(2001)3:1<41:ROIISA>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
STIMULATORY FACTOR INTERLEUKIN-12; TYPE-1 CYTOKINE RESPONSES; TUMOR-NECROSIS-FACTOR; INTERFERON-GAMMA; SEPTIC ARTHRITIS; IFN-GAMMA; INFECTIOUS ARTHRITIS; IL-12-DEFICIENT MICE; CALMETTE-GUERIN; PROTECTS MICE;
Keywords:
IL-12; septic arthritis; Staphylococcus aureus;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Hultgren, OH Gothenburg Univ, Dept Rheumatol, Guldhedsgatan 10, S-41346 Gothenburg, Sweden Gothenburg Univ Guldhedsgatan 10 Gothenburg Sweden S-41346 n
Citazione:
O.H. Hultgren et al., "Role of IL-12 in Staphylococcus aureus-triggered arthritis and sepsis", ARTHRITIS R, 3(1), 2001, pp. 41-47

Abstract

The present study demonstrates that endogenous production of IL-12 is crucial for survival in Staphylococcus aureus-induced arthritis in mice. Staphylococcal load is enhanced in several organs, because of lack of IL-12. Thismight be due to decreased production of IFN-gamma in IL-12-deficient mice. Although IL-12-deficient mice were exposed to higher staphylococcal load, they demonstrated no increased severity of arthritis as compared with control animals.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 07:31:13