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Titolo:
Physical activity and risk of cognitive impairment and dementia in elderlypersons
Autore:
Laurin, D; Verreault, R; Lindsay, J; MacPherson, K; Rockwood, K;
Indirizzi:
Univ Laval, Ctr Hosp Affilie Univ Quebec, Ctr Hebergement St Augustin, Geriatr Res Unit, Beauport, PQ G1C 1Z2, Canada Univ Laval Beauport PQ Canada G1C 1Z2 Unit, Beauport, PQ G1C 1Z2, Canada Univ Laval, Dept Social & Prevent Med, St Foy, PQ G1K 7P4, Canada Univ Laval St Foy PQ Canada G1K 7P4 event Med, St Foy, PQ G1K 7P4, Canada Univ Ottawa, Dept Epidemiol & Community Med, Ottawa, ON, Canada Univ Ottawa Ottawa ON Canada idemiol & Community Med, Ottawa, ON, Canada Hlth Canada, Aging Related Dis Div, Lab Ctr Dis Control, Ottawa, ON K1A 0L2, Canada Hlth Canada Ottawa ON Canada K1A 0L2 Control, Ottawa, ON K1A 0L2, Canada Dalhousie Univ, Dept Epidemiol & Community Hlth, Halifax, NS, Canada Dalhousie Univ Halifax NS Canada l & Community Hlth, Halifax, NS, Canada Dalhousie Univ, Queen Elizabeth II Hlth Sci Ctr, Div Geriatr Med, Halifax,NS, Canada Dalhousie Univ Halifax NS Canada tr, Div Geriatr Med, Halifax,NS, Canada
Titolo Testata:
ARCHIVES OF NEUROLOGY
fascicolo: 3, volume: 58, anno: 2001,
pagine: 498 - 504
SICI:
0003-9942(200103)58:3<498:PAAROC>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLACEBO-CONTROLLED TRIAL; AGE-RELATED DEMENTIA; ALZHEIMERS-DISEASE; DOUBLE-BLIND; OLDER WOMEN; NEUROPSYCHOLOGICAL FUNCTION; REPLACEMENT THERAPY; GERIATRIC-MEDICINE; VASCULAR DEMENTIA; AEROBIC EXERCISE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: Verreault, R Univ Laval, Ctr Hosp Affilie Univ Quebec, Ctr Hebergement St Augustin, Geriatr Res Unit, Beauport, PQ G1C 1Z2, Canada Univ Laval Beauport PQ Canada G1C 1Z2 rt, PQ G1C 1Z2, Canada
Citazione:
D. Laurin et al., "Physical activity and risk of cognitive impairment and dementia in elderlypersons", ARCH NEUROL, 58(3), 2001, pp. 498-504

Abstract

Context: Dementia is common, costly, and highly age related. Little attention has been paid to the identification;of modifiable lifestyle habits for its prevention. Objective: To explore the association between physical activity and the risk of cognitive impairment and dementia. Design, Setting, and Subjects: Data come from a community sample of 9008 randomly selected men and women 65 years or older, who were evaluated in the1991-1992 Canadian Study of Health and Aging, a prospective cohort study of dementia. Of the 6434 eligible subjects who were cognitively normal at baseline, 4615 completed a 5-year follow-up. Screening and clinical evaluations were done at both waves of the study. In 1996-1997, 3894 remained without cognitive impairment, 436 were diagnosed as having cognitive impairment-no dementia, and 285 were diagnosed as having dementia. Main Outcome Measure: Incident cognitive impairment and dementia by levelsof physical activity at baseline. Results: Compared with no exercise, physical activity was associated with lower risks of cognitive impairment, Alzheimer disease, and dementia of anytype. Significant trends for increased protection with greater physical activity were observed. High levels of physical activity were associated withreduced risks of cognitive impairment (age-, sex-, and education-adjusted odds ratio, 0.58; 95% confidence interval, 0.41-0.83), Alzheimer disease (odds ratio, 0.50; 95% confidence interval, 0.28-0.90), and dementia of any type (odds ratio, 0.63; 95% confidence interval, 0.40-0.98). Conclusion: Regular physical activity could represent an important and potent protective factor for cognitive decline and dementia in elderly persons.

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Documento generato il 09/08/20 alle ore 22:34:07