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Titolo:
Effect of pravastatin on plasma markers of inflammation and peripheral endothelial function in male heart transplant recipients
Autore:
Holm, T; Andreassen, AK; Ueland, T; Kjekshus, J; Froland, SS; Kjekshus, E; Simonsen, S; Aukrust, P; Gullestad, L;
Indirizzi:
Univ Oslo, Rikshosp, Dept Cardiol, Internal Med Res Inst, N-0027 Oslo, Norway Univ Oslo Oslo Norway N-0027 Internal Med Res Inst, N-0027 Oslo, Norway Univ Oslo, Rikshosp, Dept Med, Sect Clin Immunol & Infect Dis, N-0027 Oslo, Norway Univ Oslo Oslo Norway N-0027 n Immunol & Infect Dis, N-0027 Oslo, Norway
Titolo Testata:
AMERICAN JOURNAL OF CARDIOLOGY
fascicolo: 6, volume: 87, anno: 2001,
pagine: 815 -
SICI:
0002-9149(20010315)87:6<815:EOPOPM>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
SKIN MICROCIRCULATION; TNF-ALPHA; DYSFUNCTION; RECEPTORS; CYTOKINES; CORONARY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Holm, T Univ Oslo, Rikshosp, Dept Cardiol, Internal Med Res Inst, N-0027 Oslo, Norway Univ Oslo Oslo Norway N-0027 l Med Res Inst, N-0027 Oslo, Norway
Citazione:
T. Holm et al., "Effect of pravastatin on plasma markers of inflammation and peripheral endothelial function in male heart transplant recipients", AM J CARD, 87(6), 2001, pp. 815

Abstract

Statins appear to have several biologic effects beyond those of lipid metabolism, and we hypothesized that immunomodulating effects of statins are important for the beneficial effects of these medications after heart transplantation. Our findings suggest that pravastatin treatment reduces plasma markers of inflammation and improves peripheral endothelial function in hearttransplant recipients, possibly contributing to the observed clinical benefits of statin treatment in these patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 07:21:34